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Vassilis Pachnis Publications

Lopes, R; Verhey van Wijk, N; Neves, G and Pachnis, V (2012)
Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum.
Proceedings of the National Academy of Sciences of the United States of America 109, 3119-3124
Sasselli, V; Pachnis, V and Burns, AJ (2012)
The enteric nervous system.
Developmental Biology [Epub ahead of print] PubMed abstract
Vidaki, M; Tivodar, S; Doulgeraki, K; Tybulewicz, V; Kessaris, N; Pachnis, V and Karagogeos, D (2012)
Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex.
Cerebral Cortex 22, 680-692 PubMed abstract
Heanue, TA and Pachnis, V (2011)
Prospective identification and isolation of enteric nervous system progenitors using Sox2.
Stem Cells 29, 128-140 PubMed abstract
Laranjeira, C; Sandgren, K; Kessaris, N; Richardson, W; Potocnik, A; Vanden Berghe, P and Pachnis, V (2011)
Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.
The Journal of clinical investigation 121, 3412-3424 PubMed abstract
Spella, M; Kyrousi, C; Kritikou, E; Stathopoulou, A; Guillemot, F; Kioussis, D; Pachnis, V; Lygerou, Z and Taraviras, S (2011)
Geminin regulates cortical progenitor proliferation and differentiation.
Stem Cells 29, 1269-1282 PubMed abstract
Karamitros, D; Kotantaki, P; Lygerou, Z; Veiga-Fernandes, H; Pachnis, V; Kioussis, D and Taraviras, S (2010)
Differential Geminin requirement for proliferation of thymocytes and mature T cells.
Journal of Immunology 184, 2432-2441 PubMed abstract
Karamitros, D; Kotantaki, P; Lygerou, Z; Veiga-Fernandes, H; Pachnis, V; Kioussis, D and Taraviras, S (2010)
Life without geminin.
Cell Cycle 9, 3181-3185 PubMed abstract
Batista-Brito, R; Rossignol, E; Hjerling-Leffler, J; Denaxa, M; Wegner, M; Lefebvre, V; Pachnis, V and Fishell, G (2009)
The cell-intrinsic requirement of Sox6 for cortical interneuron development.
Neuron 63, 466-481 PubMed abstract
Burns, AJ and Pachnis, V (2009)
Development of the enteric nervous system: bringing together cells, signals and genes.
Neurogastroenterology and Motility 21, 100-102 PubMed abstract
Denaxa, M; Sharpe, PT and Pachnis, V (2009)
The LIM-Homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition.
Developmental Biology 333, 324-336 PubMed abstract
Fragkouli, A; Pachnis, V and Stylianopoulou, F (2009)
Sex differences in water maze performance and cortical neurotrophin levels of Lhx7 null mutant mice.
Neuroscience 158, 1224-1233 PubMed abstract
Fragkouli, A; van Wijk, NV; Lopes, R; Kessaris, N and Pachnis, V (2009)
LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons.
Development 136, 3841-3851 PubMed abstract
Kioussis, D and Pachnis, V (2009)
Immune and nervous systems: more than just a superficial similarity?
Immunity 31, 705-710 PubMed abstract
Laranjeira, C and Pachnis, V (2009)
Enteric nervous system development: recent progress and future challenges.
Autonomic Neuroscience: Basic and Clinical 151, 61-69 PubMed abstract
Skuntz, S; Mankoo, B; Nguyen, MT; Hustert, E; Nakayama, A; Tournier-Lasserve, E; Wright, CVE; Pachnis, V; Bharti, K and Arnheiter, H (2009)
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.
Developmental Biology 332, 383-395 PubMed abstract
Bogni, S; Trainor, P; Natarajan, D; Krumlauf, R and Pachnis, V (2008)
Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis.
Development 135, 3007-3011 PubMed abstract
Foster, K; Sheridan, J; Veiga-Fernandes, H; Roderick, K; Pachnis, V; Adams, R; Blackburn, C; Kioussis, D and Coles, M (2008)
Contribution of neural crest-derived cells in the embryonic and adult thymus.
Journal of Immunology 180, 3183-3189 PubMed abstract
Heanue, TA and Pachnis, V (2008)
Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species.
Mechanisms of Development 125, 687-699 PubMed abstract
Butt, SJB; Cobos, I; Golden, J; Kessaris, N; Pachnis, V and Anderson, S (2007)
Transcriptional regulation of cortical interneuron development.
Journal of Neuroscience 27, 11847-11850 PubMed abstract
Fogarty, M; Grist, M; Gelman, D; Marin, O; Pachnis, V and Kessaris, N (2007)
Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex.
Journal of Neuroscience 27, 10935-10946 PubMed abstract
Heanue, TA and Pachnis, V (2007)
Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies.
Nature Reviews Neuroscience 8, 466-479 PubMed abstract
Liodis, P; Denaxa, M; Grigoriou, M; Akufo-Addo, C; Yanagawa, Y and Pachnis, V (2007)
Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes.
Journal of Neuroscience 27, 3078-3089 PubMed abstract
Veiga-Fernandes, H; Coles, MC; Foster, KE; Patel, A; Williams, A; Natarajan, D; Barlow, A; Pachnis, V and Kioussis, D (2007)
Tyrosine kinase receptor RET is a key regulator of Peyer's Patch organogenesis.
Nature 446, 547-551 PubMed abstract
Asai, N; Fukuda, T; Wu, Z; Enomoto, A; Pachnis, V; Takahashi, M and Costantini, F (2006)
Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Development 133, 4507-4516 PubMed abstract
Bondurand, N; Natarajan, D; Barlow, A; Thapar, N and Pachnis, V (2006)
Maintenance of mammalian enteric nervous system progenitors by SOX10 and endothelin 3 signalling.
Development 133, 2075-2086 PubMed abstract
Cassiman, D; Barlow, A; Vander Borght, S; Libbrecht, L and Pachnis, V (2006)
Hepatic stellate cells do not derive from the neural crest.
Journal of Hepatology 44, 1098-1104 PubMed abstract
Fragkouli, A; Stamatakis, A; Zographos, E; Pachnis, V and Stylianopoulou, F (2006)
Sexually dimorphic effects of the LHX7 null mutation on forebrain cholinergic function.
Neuroscience 137, 1153-1164 PubMed abstract
Heanue, TA and Pachnis, V (2006)
Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes.
Proceedings of the National Academy of Sciences of the United States of America 103, 6919-6924 PubMed abstract
Heuckeroth, RO and Pachnis, V (2006)
Getting to the guts of enteric nervous system development.
Development 133, 2287-2290 PubMed abstract
Stanchina, L; Baral, V; Robert, F; Pingault, V; Lemort, N; Pachnis, V; Goossens, M and Bondurand, N (2006)
Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development.
Developmental Biology 295, 232-249 PubMed abstract