MRC National Institute for Medical Research, London
Science for Health
Steve Gamblin Publications
- Hu, H; Voss, J; Zhang, G; Buchy, P; Zuo, T; Wang, L; Wang, F; Zhou, F; Wang, G; Tsai, C; Calder, L; Gamblin, SJ; Zhang, L; Deubel, V; Zhou, B; Skehel, JJ and Zhou, P (2012)
A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.
Journal of Virology 86, 2978-2989 PubMed abstract - Carling, D; Mayer, FV; Sanders, MJ and Gamblin, SJ (2011)
AMP-activated protein kinase: nature's energy sensor.
Nature Chemical Biology 7, 512-518 PubMed abstract - Corti, D; Voss, J; Gamblin, SJ; Codoni, G; Macagno, A; Jarrossay, D; Vachieri, SG; Pinna, D; Minola, A; Vanzetta, F; Silacci, C; Fernandez-Rodriguez, BM; Agatic, G; Bianchi, S; Giacchetto-Sasselli, I; Calder, L; Sallusto, F; Collins, P; Haire, LF; Temperton, N; Langedijk, JPM; Skehel, JJ and Lanzavecchia, A (2011)
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.
Science 333, 850-856 PubMed abstract - Hardie, DG; Carling, D and Gamblin, SJ (2011)
AMP-activated protein kinase: also regulated by ADP?
Trends in Biochemical Sciences 36, 470-477 PubMed abstract - Mayer, FV; Heath, R; Underwood, E; Sanders, MJ; Carmena, D; McCartney, RR; Leiper, FC; Xiao, B; Jing, C; Walker, PA; Haire, LF; Ogrodowicz, R; Martin, SR; Schmidt, MC; Gamblin, SJ and Carling, D (2011)
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase.
Cell Metabolism 14, 707-714 PubMed abstract - Xiao, B; Sanders, MJ; Underwood, E; Heath, R; Mayer, FV; Carmena, D; Jing, C; Walker, PA; Eccleston, JF; Haire, LF; Saiu, P; Howell, SA; Aasland, R; Martin, SR; Carling, D and Gamblin, SJ (2011)
Structure of mammalian AMPK and its regulation by ADP.
Nature 472, 230-233 PubMed abstract - Gamblin, SJ and Skehel, JJ (2010)
Influenza haemagglutinin and neuraminidase membrane glycoproteins.
Journal of Biological Chemistry 285, 28403-28409 PubMed abstract - Justin, N; De Marco, V; Aasland, R and Gamblin, SJ (2010)
Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies.
Current Opinion in Structural Biology 20, 730-738 PubMed abstract - Spencer, J; Murphy, LM; Conners, R; Sessions, RB and Gamblin, SJ (2010)
Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: Substrate specificity and mechanism of M23 metallopeptidases.
Journal of Molecular Biology 396, 908-923 PubMed abstract - Collins, PJ; Haire, LF; Lin, YP; Liu, J; Russell, RJ; Walker, PA; Martin, SR; Daniels, RS; Gregory, V; Skehel, JJ; Gamblin, SJ and Hay, AJ (2009)
Structural basis for oseltamivir resistance of influenza viruses.
Vaccine 27, 6317-6323 PubMed abstract - Liu, J; Stevens, DJ; Haire, LF; Walker, PA; Coombs, PJ; Russell, RJ; Gamblin, SJ and Skehel, JJ (2009)
Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957.
Proceedings of the National Academy of Sciences of the United States of America 106, 17175-17180 PubMed abstract - Margueron, R; Justin, N; Ohno, K; Sharpe, ML; Son, J; Drury III, WJ; Voigt, P; Martin, SR; Taylor, WR; De Marco, V; Pirrotta, V; Reinberg, D and Gamblin, SJ (2009)
Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature 461, 762-767 PubMed abstract - Collins, PJ; Haire, LF; Lin, YP; Liu, J; Russell, RJ; Walker, PA; Skehel, JJ; Martin, SR; Hay, AJ and Gamblin, SJ (2008)
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature 453, 1258-1261 PubMed abstract - Russell, RJ; Kerry, PS; Stevens, DJ; Steinhauer, DA; Martin, SR; Gamblin, SJ and Skehel, JJ (2008)
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.
Proceedings of the National Academy of Sciences of the United States of America 105, 17736-17741 PubMed abstract - Xiao, B; Heath, R; Saiu, P; Leiper, FC; Leone, P; Jing, C; Walker, PA; Haire, L; Eccleston, JF; Davis, CT; Martin, SR; Carling, D and Gamblin, SJ (2007)
Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Nature 449, 496-500 PubMed abstract - Russell, RJ; Haire, LF; Stevens, DJ; Collins, PJ; Lin, YP; Blackburn, GM; Hay, AJ; Gamblin, SJ and Skehel, JJ (2006)
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature 443, 45-49 PubMed abstract - Russell, RJ; Stevens, DJ; Haire, LF; Gamblin, SJ and Skehel, JJ (2006)
Avian and human receptor binding by hemagglutinins of influenza A viruses.
Glycoconjugate Journal 23, 85-92 PubMed abstract - Yamada, S; Suzuki, Y; Suzuki, T; Le, MQ; Nidom, CA; Sakai-Tagawa, Y; Muramoto, Y; Ito, M; Kiso, M; Horimoto, T; Shinya, K; Sawada, T; Kiso, M; Usui, T; Murata, T; Lin, YP; Hay, A; Haire, LF; Stevens, DJ; Russell, RJ; Gamblin, SJ; Skehel, JJ and Kawaoka, Y (2006)
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.
Nature 444, 378-382 PubMed abstract
[Page last updated 1 May 2012]
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