MRC National Institute for Medical Research, London

Robert Wilkinson Publications

• Bond, E; Liang, F; Sandgren, KJ; Smed-Sörensen, A; Bergman, P; Brighenti, S; Adams, WC; Betemariam, SA; Rangaka, MX; Lange, C; Wilkinson, RJ; Andersson, J and Loré, K (2012)
  Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.
  Journal of Investigative Dermatology 132, 114-123 PubMed abstract
• Lowe, DM; Redford, PS; Wilkinson, RJ; O'Garra, A and Martineau, AR (2012)
  Neutrophils in tuberculosis: friend or foe?
  Trends in Immunology 33, 14-25 PubMed abstract
• Rangaka, MX; Gideon, HP; Wilkinson, KA; Pai, M; Mwansa-Kambafilwe, J; Maartens, G; Glynn, JR; Boulle, A; Fielding, K; Goliath, R; Titus, R; Mathee, S and Wilkinson, RJ (2012)
  No discriminatory value of interferon release added to smear negative HIV-tuberculosis algorithms.
  European Respiratory Journal 39, 163-171 PubMed abstract
• Rangaka, MX; Gideon, HP; Wilkinson, KA; Pai, M; Mwansa-Kambafwile, J; Maartens, G; Glynn, JR; Boulle, A; Fielding, K; Goliath, R; Titus, R; Mathee, S and Wilkinson, RJ (2012)
  Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms.
  European Respiratory Journal 39, 163-171 PubMed abstract
• Rangaka, MX; Wilkinson, KA; Glynn, JR; Ling, D; Menzies, D; Mwansa-Kambafwile, J; Fielding, K; Wilkinson, RJ and Pai, M (2012)
  Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis.
  Lancet Infectious Diseases 12, 45-55 PubMed abstract
• Wilkinson, RJ (2012)
  Human genetic susceptibility to tuberculosis: time for a bottom-up approach?
  Journal of Infectious Diseases 205, 525-527
• Dodd, LE and Wilkinson, RJ (2011)
  Isoniazid preventive therapy in HIV infection.
  Lancet 377, 1548-1550 PubMed abstract
• Esmail, H; Barry, CE, 3rd and Wilkinson, RJ (2011)
  Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies.
  Drug Discovery Today [Epub ahead of print] PubMed abstract
• Jones, GJ; Pirson, C; Gideon, HP; Wilkinson, KA; Sherman, DR; Wilkinson, RJ; Hewinson, RG and Vordermeier, HM (2011)
  Immune responses to the Enduring Hypoxic Response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology.
  PLoS ONE 6, e21371 PubMed abstract
• Marais, S; Pepper, DJ; Schutz, C; Wilkinson, RJ and Meintjes, G (2011)
  Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting.
  PLoS ONE 6, e20077 PubMed abstract
• Martineau, AR; Nhamoyebonde, S; Oni, T; Rangaka, MX; Marais, S; Bangani, N; Tsekela, R; Bashe, L; de Azevedo, V; Caldwell, J; Venton, TR; Timms, PM; Wilkinson, KA and Wilkinson, RJ (2011)
  Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa.
  Proceedings of the National Academy of Sciences 1058, 19013-19017 PubMed abstract
• Martineau, AR; Timms, PM; Bothamley, GH; Hanifa, Y; Islam, K; Claxton, AP; Packe, GE; Moore-Gillon, JC; Darmalingam, M; Davidson, RN; Milburn, HJ; Baker, LV; Barker, RD; Woodward, NJ; Venton, TR; Barnes, KE; Mullett, CJ; Coussens, AK; Rutterford, CM; Mein, CA; Davies, GR; Wilkinson, RJ; Nikolayevskyy, V; Drobniewski, FA; Eldridge, SM and Griffiths, CJ (2011)
  High-dose vitamin D₃ during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial.
  Lancet 377, 242-250 PubMed abstract
• Matthews, K; Ntsekhe, M; Syed, F; Scriba, T; Russell, J; Tibazarwa, K; Deffur, A; Hanekom, W; Mayosi, BM; Wilkinson, RJ and Wilkinson, KA (2011)
  HIV-1 infection alters CD4⁺ memory T cell phenotype at the site of disease in extrapulmonary tuberculosis.
  European Journal of Immunology 42, 147-157 PubMed abstract
• Matthews, K; Wilkinson, KA; Kalsdorf, B; Roberts, T; Diacon, A; Walzl, G; Wolske, J; Ntsekhe, M; Syed, F; Russell, J; Mayosi, BM; Dawson, R; Dheda, K; Wilkinson, RJ; Hanekom, WA and Scriba, TJ (2011)
  Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis.
  Tuberculosis 91, 587-593 PubMed abstract
• McNab, FW; Berry, MPR; Graham, CM; Bloch, SAA; Oni, T; Wilkinson, KA; Wilkinson, RJ; Kon, OM; Banchereau, J; Chaussabel, D and O'Garra, A (2011)
  Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis.
  European Journal of Immunology 41, 1941-1947 PubMed abstract
• Oni, T; Burke, R; Tsekela, R; Bangani, N; Seldon, R; Gideon, HP; Wood, K; Wilkinson, KA; Ottenhoff, THM and Wilkinson, RJ (2011)
  High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening.
  Thorax 66, 669-673 PubMed abstract
• Pepper, DJ; Marais, S; Wilkinson, RJ; Bhaijee, F; De Azevedo, V and Meintjes, G (2011)
  Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa.
  PLoS ONE 6, e1984 PubMed abstract
• Tadokera, R; Meintjes, G; Skolimowska, KH; Wilkinson, KA; Matthews, K; Seldon, R; Chegou, NN; Maartens, G; Rangaka, MX; Rebe, K; Walzl, G and Wilkinson, RJ (2011)
  Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
  European Respiratory Journal 37, 1248-1259 PubMed abstract
• Asselman, V; Thienemann, F; Pepper, DJ; Boulle, A; Wilkinson, RJ; Meintjes, G and Marais, S (2010)
  Central nervous system disorders after starting antiretroviral therapy in South Africa.
  AIDS 24, 2871-2876 PubMed abstract
• Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2010)
  Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes: authors' reply.
  Nature Reviews Microbiology 8, 242
• Berry, MPR; Graham, CM; McNab, FW; Xu, Z; Bloch, SAA; Oni, T; Wilkinson, KA; Banchereau, R; Skinner, J; Wilkinson, RJ; Quinn, C; Blankenship, D; Dhawan, R; Cush, JJ; Mejias, A; Ramilo, O; Kon, OM; Pascual, V; Banchereau, J; Chaussabel, D and O'Garra, A (2010)
  An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.
  Nature 466, 973-977 PubMed abstract
• Bhaijee, F; Wainwright, H; Meintjes, G; Wilkinson, RJ; Todd, G; de Vries, E and Pepper, DJ (2010)
  Warfarin-induced skin necrosis in HIV-1-infected patients with tuberculosis and venous thrombosis.
  South African Medical Journal 100, 372-377 PubMed abstract
• Chatterjee, A; D'Souza, D; Vira, T; Bamne, A; Ambe, GT; Nicol, MP; Wilkinson, RJ and Mistry, N (2010)
  Strains of Mycobacterium tuberculosis from Western Maharashtra, India exhibit a high degree of diversity and strain-specific associations with drug resistance, cavitary disease and treatment failure.
  Journal of Clinical Microbiology 48, 3593-3599 PubMed abstract
• Chun, RF; Lauridsen, AL; Suon, L; Zella, LA; Pike, JW; Modlin, RL; Martineau, AR; Wilkinson, RJ; Adams, J and Hewison, M (2010)
  Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D.
  Journal of Clinical Endocrinology and Metabolism 95, 3368-3376 PubMed abstract
• Connell, TG; Davies, MA; Johannisen, C; Wood, K; Pienaar, S; Wilkinson, KA; Wilkinson, RJ; Zar, HJ; Beatty, D; Nicol, MP; Curtis, N and Eley, B (2010)
  Reversion and conversion of Mycobacterium tuberculosis IFN-γ ELISpot results during anti-tuberculous treatment in HIV-infected children.
  BMC Infectious Diseases 10, 138 PubMed abstract
• Gideon, HP; Wilkinson, KA; Rustad, TR; Oni, T; Guio, H; Kozak, RA; Sherman, DR; Meintjes, G; Behr, MA; Vordermeier, HM; Young, DB and Wilkinson, RJ (2010)
  Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
  PLoS Pathogens 6, e1001237 PubMed abstract
• Lange, C and Wilkinson, RJ (2010)
  Vitamin D and active tuberculosis: a futile quest?
  American Journal of Respiratory and Critical Care Medicine 181, 95
• Lawn, SD and Wilkinson, RJ (2010)
  Primate model to study reactivation of TB associated with retroviral infection.
  Future Virology 5, 391-395
• Lawn, SD; Wood, R and Wilkinson, RJ (2010)
  Changing concepts of "latent tuberculosis infection" in patients living with HIV infection.
  Clinical & Developmental Immunology 2011, 980594 PubMed abstract
• Marais, S; Scholtz, P; Pepper, DJ; Meintjes, G; Wilkinson, RJ and Candy, S (2010)
  Neuroradiological features of the tuberculosis-associated immune reconstitution inflammatory syndrome.
  International Journal of Tuberculosis and Lung Disease 14, 188-196 PubMed abstract
• Marais, S; Thwaites, G; Schoeman, JF; Török, ME; Misra, UK; Prasad, K; Donald, PR; Wilkinson, RJ and Marais, BJ (2010)
  Tuberculous meningitis: a uniform case definition for use in clinical research.
  Lancet Infectious Diseases 10, 803-812 PubMed abstract
• Martineau, AR; Leandro, ACCS; Anderson, ST; Newton, SM; Wilkinson, KA; Nicol, MP; Pienaar, SM; Skolimowska, KH; Rocha, MA; Rolla, VC; Levin, M; Davidson, RN; Bremner, SA; Griffiths, CJ; Eley, BS; Bonecini-Almeida, MG and Wilkinson, RJ (2010)
  Association between Gc genotype and susceptibility to TB is dependent on vitamin D status.
  European Respiratory Journal 35, 1106-1112 PubMed abstract
• Meintjes, G and Wilkinson, RJ (2010)
  Optimum timing of antiretroviral therapy for HIV-infected patients with concurrent serious opportunistic infections.
  Clinical Infectious Diseases 50, 1539-1541 PubMed abstract
• Meintjes, G and Wilkinson, RJ (2010)
  Undiagnosed active tuberculosis in HIV-infected patients commencing antiretroviral therapy.
  Clinical Infectious Diseases 51, 830-832 PubMed abstract
• Meintjes, G; Wilkinson, RJ; Morroni, C; Pepper, DJ; Rebe, K; Rangaka, MX; Oni, T and Maartens, G (2010)
  Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome.
  AIDS 24, 2381-2390 PubMed abstract
• Oni, T; Patel, J; Gideon, HP; Seldon, R; Wood, K; Hlombe, Y; Wilkinson, KA; Rangaka, MX; Mendelson, M and Wilkinson, RJ (2010)
  Enhanced diagnosis of HIV-1 associated tuberculosis by relating T-SPOT.TB and CD4 counts.
  European Respiratory Journal 36, 594-600 PubMed abstract
• Pepper, DJ; Marais, S; Wilkinson, RJ; Bhaijee, F; Maartens, G; McIlleron, H; De Azevedo, V; Cox, H; McDermid, C; Sokhela, S; Patel, J and Meintjes, G (2010)
  Clinical deterioration during anti-tuberculosis treatment in Africa: Incidence, causes and risk factors.
  BMC Infectious Diseases 10, 83 PubMed abstract
• Schutz, C; Meintjes, G; Almajid, F; Wilkinson, RJ and Pozniak, A (2010)
  Clinical management of tuberculosis and HIV-1 co-infection.
  European Respiratory Journal 36, 1460-1481 PubMed abstract
• Tena-Coki, NG; Scriba, TJ; Peteni, N; Eley, B; Wilkinson, RJ; Andersen, P; Hanekom, WA and Kampmann, B (2010)
  CD4 and CD8 T cell responses to mycobacterial antigens in African children.
  American Journal of Respiratory and Critical Care Medicine 182 , 120-129 PubMed abstract
• Wilkinson, KA and Wilkinson, RJ (2010)
  Polyfunctional T cells in human tuberculosis.
  European Journal of Immunology 40, 2139-2142 PubMed abstract
• Wood, R; Liang, H; Wu, H; Middelkoop, K; Oni, T; Rangaka, MX; Wilkinson, RJ; Bekker, L-G and Lawn, SD (2010)
  Changing prevalence of tuberculosis infection with increasing age in high-burden townships in South Africa.
  International Journal of Tuberculosis and Lung Disease 14, 406-412 PubMed abstract
• Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2009)
  The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
  Nature Reviews Microbiology 7, 845-855 PubMed abstract
• Berry, MPR; Graham, CM; Bloch, SJ; Oni, T; Wilkinson, KA; Wilkinson, RJ; Kon, OM; Banchereau, J; Chaussabel, D and O'Garra, A (2009)
  Systems biology approaches characterise the host response to tuberculosis.
  Thorax 64, A10-A13
• Davies, MA; Connell, T; Johannisen, C; Wood, K; Pienaar, S; Wilkinson, KA; Wilkinson, RJ; Zar, HJ; Eley, B; Beatty, D; Curtis, N and Nicol, MP (2009)
  Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.
  AIDS 23, 961-969 PubMed abstract
• Dsouza, DTB; Mistry, NF; Vira, TS; Dholakia, Y; Hoffner, S; Pasvol, G; Nicol, M and Wilkinson, RJ (2009)
  High levels of multidrug resistant tuberculosis in new and treatment-failure patients from the Revised National Tuberculosis Control Programme in an urban metropolis (Mumbai) in Western India.
  BMC Public Health 9, 211 PubMed abstract
• Kalsdorf, B; Scriba, TJ; Wood, K; Day, CL; Dheda, K; Dawson, R; Hanekom, WA; Lange, C and Wilkinson, RJ (2009)
  HIV-1 infection impairs the bronchoalveolar T cell response to mycobacteria.
  American Journal of Respiratory and Critical Care Medicine 180, 1262-1270 PubMed abstract
• Marais, S; Wilkinson, RJ; Pepper, DJ and Meintjes, G (2009)
  Management of patients with the immune reconstitution inflammatory syndrome.
  Current HIV/AIDS reports 6, 162-171 PubMed abstract
• Martineau, AR; Nanzer, AM; Satkunam, KR; Packe, GE; Rainbow, SJ; Maunsell, ZJ; Timms, PM; Venton, TR; Eldridge, SM; Davidson, RN; Wilkinson, RJ and Griffiths, CJ (2009)
  Influence of a single oral dose of vitamin D₂ on serum 25-hydroxyvitamin D concentrations in tuberculosis patients.
  International Journal of Tuberculosis and Lung Disease 13, 119-125 PubMed abstract
• Meintjes, G; Rabie, H; Wilkinson, RJ and Cotton, MF (2009)
  Tuberculosis-associated immune reconstitution inflammatory syndrome and unmasking of tuberculosis by antiretroviral therapy.
  Clinics in Chest Medicine 30, 797-810 PubMed abstract
• Nicol, MP; Davies, M-A; Wood, K; Hatherill, M; Workman, L; Hawkridge, A; Eley, B; Wilkinson, KA; Wilkinson, RJ; Hanekom, WA; Beatty, D and Hussey, G (2009)
  Comparison of T-SPOT.TB assay and tuberculin skin test for the evaluation of young children at high risk for tuberculosis in a community setting.
  Pediatrics 123, 38-43 PubMed abstract
• Pepper, DJ; Marais, S; Maartens, G; Rebe, K; Morroni, C; Rangaka, MX; Oni, T; Wilkinson, RJ and Meintjes, G (2009)
  Neurologic manifestations of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome: a case series.
  Clinical Infectious Diseases 48, E96-E107 PubMed abstract
• Pepper, DJ; Rebe, K; Morroni, C; Wilkinson, RJ and Meintjes, G (2009)
  Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses.
  PLoS ONE 4, e4520 PubMed abstract
• Sarrazin, H; Wilkinson, KA; Andersson, J; Rangaka, MX; Radler, L; van Veen, K; Lange, C and Wilkinson, RJ (2009)
  Association between tuberculin skin test reactivity, the memory CD4 cell subset, and circulating FoxP3-expressing cells in HIV-infected persons.
  Journal of Infectious Diseases 199, 702-710 PubMed abstract
• Schafer, G; Jacobs, M; Wilkinson, RJ and Brown, GD (2009)
  Non-opsonic recognition of Mycobacterium tuberculosis by phagocytes.
  Journal of Innate Immunity 1, 231-243 PubMed abstract
• Wilkinson, KA; Newton, SM; Stewart, GR; Martineau, AR; Patel, J; Sullivan, SM; Herrmann, JL; Neyrolles, O; Young, DB and Wilkinson, RJ (2009)
  Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis.
  BMC Microbiology 9, 93 PubMed abstract
• Wilkinson, KA; Seldon, R; Meintjes, G; Rangaka, MX; Hanekom, WA; Maartens, G and Wilkinson, RJ (2009)
  Dissection of regenerating T cell responses against tuberculosis in HIV infected adults sensitized by Mycobacterium tuberculosis.
  American Journal of Respiratory and Critical Care Medicine 180, 674-683 PubMed abstract
• Wilkinson, RJ and Lange, C (2009)
  Vitamin D and tuberculosis: new light on a potent biologic therapy?
  American Journal of Respiratory and Critical Care Medicine 179, 740-742 PubMed abstract
• Young, DB; Gideon, HP and Wilkinson, RJ (2009)
  Eliminating latent tuberculosis.
  Trends in Microbiology 17, 183-188 PubMed abstract
• Chege, GK; Warren, RW; Gey van Pittius, NC; Burgers, WA; Wilkinson, RJ; Shephard, EG and Williamson, A-L (2008)
  Detection of natural infection with Mycobacterium intracellulare in healthy wild-caught Chacma baboons (Papio ursinus) by ESAT-6 and CFP-10 IFN-γ ELISPOT tests following a tuberculosis outbreak.
  BMC Microbiology 8, 27 PubMed abstract
• Coussens, A; Timms, PM; Boucher, BJ; Venton, TR; Ashcroft, AT; Skolimowska, KH; Newton, SM; Wilkinson, KA; Davidson, RN; Griffiths, CJ; Wilkinson, RJ and Martineau, AR (2008)
  1α,25-dihydroxyvitamin D₃ inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection.
  Immunology 127, 539-548 PubMed abstract
• Cowley, D; Govender, D; February, B; Wolfe, M; Steyn, L; Evans, J; Wilkinson, RJ and Nicol, MP (2008)
  Recent and rapid emergence of W-Beijing strains of Mycobacterium tuberculosis in Cape Town, South Africa.
  Clinical Infectious Diseases 47, 1252-1259 PubMed abstract
• Dhasmana, DJ; Dheda, K; Ravn, P; Wilkinson, RJ and Meintjes, G (2008)
  Immune reconstitution inflammatory syndrome in HIV-infected patients receiving antiretroviral therapy : pathogenesis, clinical manifestations and management.
  Drugs 68, 191-208 PubMed abstract
• Eddleston, M; Davidson, RN; Brent, AB and Wilkinson, RJ (editors).
  Oxford handbook of tropical medicine. 3rd edition.
  Oxford, Oxford University Press, 2008.
• Lawn, SD; Wilkinson, RJ; Lipman, MC and Wood, R (2008)
  Immune reconstitution and "Unmasking" of tuberculosis during antiretroviral therapy.
  American Journal of Respiratory and Critical Care Medicine 177, 680-685 PubMed abstract
• Meintjes, G; Lawn, SD; Scano, F; Maartens, G; French, MA; Worodria, W; Elliott, JH; Murdoch, D; Wilkinson, RJ; Seyler, C; John, L; van der Loeff, MS; Reiss, P; Lynen, L; Janoff, EN; Gilks, C and Colebunders, R (2008)
  Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings.
  Lancet Infectious Diseases 8, 516-523 PubMed abstract
• Meintjes, G; Wilkinson, KA; Rangaka, MX; Skolimowska, K; van Veen, K; Abrahams, M; Seldon, R; Pepper, DJ; Rebe, K; Mouton, P; van Cutsem, G; Nicol, MP; Maartens, G and Wilkinson, RJ (2008)
  Type 1 helper T cells and FoxP3-positive T cells in HIV-tuberculosis-associated immune reconstitution inflammatory syndrome.
  American Journal of Respiratory and Critical Care Medicine 178, 1083-1089 PubMed abstract
• Newton, SM; Mackie, SL; Martineau, AR; Wilkinson, KA; Kampmann, B; Fisher, C; Dutta, S; Levin, M; Wilkinson, RJ and Pasvol, G (2008)
  Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients.
  Clinical and Vaccine Immunology 15, 506-512 PubMed abstract
• Nicol, MP and Wilkinson, RJ (2008)
  The clinical consequences of strain diversity in Mycobacterium tuberculosis.
  Transactions of the Royal Society of Tropical Medicine and Hygiene 102, 955-965 PubMed abstract
• Scriba, TJ; Kalsdorf, B; Abrahams, D-A; Isaacs, F; Hofmeister, J; Black, G; Hassan, HY; Wilkinson, RJ; Walzl, G; Gelderbloem, SJ; Mahomed, H; Hussey, GD and Hanekom, WA (2008)
  Distinct, specific IL-17- and IL-22-producing CD4⁺ T cell subsets contribute to the human anti-mycobacterial immune response.
  Journal of Immunology 180, 1962-1970 PubMed abstract
• Connell, TG; Shey, MS; Seldon, R; Rangaka, MX; van Cutsem, G; Simsova, M; Marcekova, Z; Sebo, P; Curtis, N; Diwakar, L; Meintjes, GA; Leclerc, C; Wilkinson, RJ and Wilkinson, KA (2007)
  Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector.
  Clinical and Vaccine Immunology 14, 847-854 PubMed abstract
• Henao-Tamayo, M; Junqueira-Kipnis, AP; Ordway, D; Gonzales-Juarrero, M; Stewart, GR; Young, DB; Wilkinson, RJ; Basaraba, RJ and Orme, IM (2007)
  A mutant of Mycobacterium tuberculosis lacking the 19-kDa lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties.
  Vaccine 25, 7153-7159 PubMed abstract
• Lawn, SD; Bangani, N; Vogt, M; Bekker, L-G; Badri, M; Ntobongwana, M; Dockrell, HM; Wilkinson, RJ and Wood, R (2007)
  Utility of interferon-γ ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa .
  BMC Infectious Diseases 7, 99 PubMed abstract
• Maartens, G and Wilkinson, RJ (2007)
  Tuberculosis.
  Lancet 370, 2030-2043 PubMed abstract
• Martineau, AR; Honecker, FU; Wilkinson, RJ and Griffiths, CJ (2007)
  Vitamin D in the treatment of pulmonary tuberculosis.
  Journal of Steroid Biochemistry and Molecular Biology 103, 793-798 PubMed abstract
• Martineau, AR; Newton, SM; Wilkinson, KA; Kampmann, B; Hall, BM; Nawroly, N; Packe, GE; Davidson, RN; Griffiths, CJ and Wilkinson, RJ (2007)
  Neutrophil-mediated innate immune resistance to mycobacteria.
  Journal of Clinical Investigation 117, 1988-1994 PubMed abstract
• Martineau, AR; Wilkinson, KA; Newton, SM; Floto, RA; Norman, AW; Skolimowska, K; Davidson, RN; Sorensen, OE; Kampmann, B; Griffiths, CJ and Wilkinson, RJ (2007)
  IFN-γ- and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37.
  Journal of Immunology 178, 7190-7198 PubMed abstract
• Martineau, AR; Wilkinson, RJ; Wilkinson, KA; Newton, SM; Kampmann, B; Hall, BM; Packe, GE; Davidson, RN; Eldridge, SM; Maunsell, ZJ; Rainbow, SJ; Berry, JL and Griffiths, CJ (2007)
  A single dose of vitamin D enhances immunity to mycobacteria.
  American Journal of Respiratory and Critical Care Medicine 176, 208-213 PubMed abstract
• McIlleron, H; Watkins, ML; Folb, PI; Ress, SR and Wilkinson, RJ (2007)
  Rifampin levels, interferon-gamma release and outcome in complicated pulmonary tuberculosis.
  Tuberculosis 87, 557-564 PubMed abstract
• Nicol, MP and Wilkinson, RJ (2007)
  Evidence guiding the treatment of children with mycobacterial diseases.
  Clinical Infectious Diseases 44, 1065-1066 PubMed abstract
• Pepper, DJ; Meintjes, GA; McLlleron, H and Wilkinson, RJ (2007)
  Combined therapy for tuberculosis and HIV-1: the challenge for drug discovery.
  Drug Discovery Today 12, 980-989 PubMed abstract
• Rangaka, MX; Diwakar, L; Seldon, R; Gilles, VC; Meintjes, GA; Morroni, C; Mouton, P; Shey, MS; Maartens, G; Wilkinson, KA and Wilkinson, RJ (2007)
  Clinical, immunological, and epidemiological importance of antituberculosis T cell responses in HIV-infected Africans.
  Clinical Infectious Diseases 44, 1639 - 1646 PubMed abstract
• Rangaka, MX; Wilkinson, KA; Seldon, R; Van Cutsem, G; Meintjes, GA; Morroni, C; Mouton, P; Diwakar, L; Connell, TG; Maartens, G and Wilkinson, RJ (2007)
  Effect of HIV-1 infection on T cell-based and skin test detection of tuberculosis infection.
  American Journal of Respiratory and Critical Care Medicine 175, 514 - 520 PubMed abstract
• Anderson, ST; Williams, AJ; Brown, JR; Newton, SM; Simsova, M; Nicol, MP; Sebo, P; Levin, M; Wilkinson, RJ and Wilkinson, KA (2006)
  Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
  American Journal of Respiratory and Critical Care Medicine 173, 1038-1042 PubMed abstract
• Connell, TG; Rangaka, MX; Curtis, N and Wilkinson, RJ (2006)
  QuantiFERON-TB Gold: state of the art for the diagnosis of tuberculosis infection?
  Expert Review of Molecular Diagnostics 6, 663-677 PubMed abstract
• Lawn, SD and Wilkinson, R (2006)
  Extensively drug resistant tuberculosis.
  British Medical Journal 333, 559-560 PubMed abstract
• Lawn, SD and Wilkinson, RJ (2006)
  Immune reconstitution disease associated with parasitic infections following antiretroviral treatment.
  Parasite Immunology 28, 625-633 PubMed abstract
• Newton, SM; Smith, RJ; Wilkinson, KA; Nicol, MP; Garton, NJ; Staples, KJ; Stewart, GR; Wain, JR; Martineau, AR; Fandrich, S; Smallie, T; Foxwell, B; Al-Obaidi, A; Shafi, J; Rajakumar, K; Kampmann, B; Andrew, PW; Ziegler-Heitbrock, L; Barer, MR and Wilkinson, RJ (2006)
  A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion.
  Proceedings of the National Academy of Sciences of the United States of America 103, 15594-15598 PubMed abstract
• Wilkinson, KA; Kon, OM; Newton, SM; Meintjes, GA; Davidson, RN; Pasvol, G and Wilkinson, RJ (2006)
  Effect of treatment of latent tuberculosis infection on the T cell response to Mycobacterium tuberculosis antigens.
  Journal of Infectious Diseases 193, 354-359 PubMed abstract

[Page last updated 1 May 2012]