MRC National Institute for Medical Research, London

Robert Wilkinson Publications

• Decloedt, EH; Mwansa-Kambafwile, J; van der Walt, JS; McIlleron, H; Denti, P; Smith, P; Wiesner, L; Rangaka, M; Wilkinson, RJ and Maartens, G (2013)
  The pharmacokinetics of nevirapine when given with isoniazid in South African HIV-infected individuals.
  International Journal of Tuberculosis and Lung Disease 17, 333-335 PubMed abstract
• Dodd, LE and Wilkinson, RJ (2013)
  Diagnosis of paediatric tuberculosis: the culture conundrum.
  The Lancet Infectious Diseases 13, 36-42 PubMed abstract
• Kalsdorf, B; Skolimowska, KH; Scriba, TJ; Dawson, R; Dheda, K; Wood, K; Hofmeister, J; Hanekom, WA; Lange, C and Wilkinson, RJ (2013)
  Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis.
  European Journal of Immunology 43, 540-549 PubMed abstract
• Liang, F; Bond, E; Sandgren, KJ; Smed-Sörensen, A; Rangaka, MX; Lange, C; Koup, RA; McComsey, GA; Lederman, MM; Wilkinson, RJ; Andersson, J and Loré, K (2013)
  Dendritic cell recruitment in response to skin antigen tests in HIV-1 infected individuals correlates with the level of T cell infiltration.
  AIDS [Epub ahead of print] PubMed abstract
• Marais, S; Meintjes, G; Pepper, DJ; Dodd, LE; Schutz, C; Ismail, Z; Wilkinson, KA and Wilkinson, RJ (2013)
  Frequency, severity and prediction of tuberculous meningitis immune reconstitution inflammatory syndrome.
  Clinical Infectious Diseases 56, 450-460 PubMed abstract
• O'Garra, A; Redford, PS; McNab, FW; Bloom, CI; Wilkinson, RJ and Berry, MPR (2013)
  The immune response in tuberculosis.
  Annual Review of Immunology 31, 475-527 PubMed abstract
• Tadokera, R; Wilkinson, KA; Meintjes, GA; Skolimowska, KH; Matthews, K; Seldon, R; Rangaka, MX; Maartens, G and Wilkinson, RJ (2013)
  Role of the interleukin 10 family of cytokines in patients with immune reconstitution inflammatory syndrome associated with HIV infection and tuberculosis .
  Journal of Infectious Diseases 207, 1148-1156 PubMed abstract
• van der Plas, H; Meintjes, G; Schutz, C; Goliath, R; Myer, L; Baatjie, D; Wilkinson, RJ; Maartens, G and Mendelson, M (2013)
  Complications of antiretroviral therapy initiation in hospitalised patients with HIV-associated tuberculosis.
  PLOS ONE 8, e54145 PubMed abstract
• Walker, NF; Meintjes, G and Wilkinson, RJ (2013)
  HIV-1 and the immune response to TB.
  Future Virology 8, 57-80
• Bloom, CI; Graham, CM; Berry, MPR; Wilkinson, KA; Oni, T; Rozakeas, F; Xu, Z; Rossello-Urgell, J; Chaussabel, D; Banchereau, J; Pascual, V; Lipman, M; Wilkinson, RJ and O'Garra, A (2012)
  Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy.
  PLOS ONE 7, e46191 PubMed abstract
• Bond, E; Liang, F; Sandgren, KJ; Smed-Sörensen, A; Bergman, P; Brighenti, S; Adams, WC; Betemariam, SA; Rangaka, MX; Lange, C; Wilkinson, RJ; Andersson, J and Loré, K (2012)
  Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.
  Journal of Investigative Dermatology 132, 114-123 PubMed abstract
• Conesa-Botella, A; Meintjes, G; Coussens, AK; van der Plas, H; Goliath, R; Schutz, C; Moreno-Reyes, R; Mehta, M; Martineau, AR; Wilkinson, RJ; Colebunders, R and Wilkinson, KA (2012)
  Corticosteroid therapy, vitamin D status, and inflammatory cytokine profile in the HIV-TB immune reconstitution inflammatory syndrome (TB-IRIS).
  Clinical Infectious Diseases 55, 1004-1011 PubMed abstract
• Coussens, AK; Wilkinson, RJ; Hanifa, Y; Nikolayevskyy, V; Elkington, PT; Islam, K; Timms, PM; Venton, TR; Bothamley, GH; Packe, GE; Darmalingam, M; Davidson, RN; Milburn, HJ; Baker, LV; Barker, RD; Mein, CA; Bhaw-Rosun, L; Nuamah, R; Young, DB; Drobniewski, FA; Griffiths, CJ and Martineau, AR (2012)
  Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.
  Proceedings of the National Academy of Sciences of the United States of America 109, 15449-15454 PubMed abstract
• Gideon, HP; Wilkinson, KA; Rustad, TR; Oni, T; Guio, H; Sherman, DR; Vordermeier, HM; Robertson, BD; Young, DB and Wilkinson, RJ (2012)
  Bioinformatic and empirical analysis of novel hypoxia-inducible targets of the human antituberculosis T cell response.
  Journal of Immunology 189, 5867-5876 PubMed abstract
• Klassen, K; Martineau, AR; Wilkinson, RJ; Cooke, G; Courtney, AP and Hickson, M (2012)
  The effect of tenofovir on vitamin D metabolism in HIV-infected adults is dependent on sex and ethnicity.
  PLOS ONE 7, e44845 PubMed abstract
• Lowe, DM; Bangani, N; Mehta, MR; Lang, DM; Rossi, AG; Wilkinson, KA; Wilkinson, RJ and Martineau, AR (2012)
  A novel assay of antimycobacterial activity and phagocytosis by human neutrophils.
  Tuberculosis 93, 167-178 PubMed abstract
• Lowe, DM; Redford, PS; Wilkinson, RJ; O'Garra, A and Martineau, AR (2012)
  Neutrophils in tuberculosis: friend or foe?
  Trends in Immunology 33, 14-25 PubMed abstract
• Meintjes, G; Skolimowska, KH; Wilkinson, KA; Matthews, K; Tadokera, R; Conesa-Botella, A; Seldon, R; Rangaka, MX; Rebe, K; Pepper, DJ; Morroni, C; Colebunders, R; Maartens, G and Wilkinson, RJ (2012)
  Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome.
  American Journal of Respiratory and Critical Care Medicine 186, 369-377 PubMed abstract
• Ntsekhe, M; Matthews, K; Wolske, J; Badri, M; Wilkinson, KA; Wilkinson, RJ; Sturrock, ED and Mayosi, BM (2012)
  Scientific letter: Ac-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline) and Galectin-3 levels in tuberculous pericardial effusion: implications for pathogenesis and prevention of pericardial constriction.
  Heart 98, 1326-1328 PubMed abstract
• Oni, T; Gideon, HP; Bangani, N; Tsekela, R; Seldon, R; Wood, K; Wilkinson, KA; Goliath, RT; Ottenhoff, TH and Wilkinson, RJ (2012)
  Risk factors associated with indeterminate interferon gamma responses in the assessment of latent tuberculosis infection in a high incidence environment.
  Clinical and Vaccine Immunology 19, 1243-1247 PubMed abstract
• Oni, T; Gideon, HP; Bangani, N; Tsekela, R; Seldon, R; Wood, K; Wilkinson, KA; Goliath, RT; Ottenhoff, THM and Wilkinson, RJ (2012)
  Smoking, BCG and employment and the risk of tuberculosis infection in HIV-infected persons in South Africa.
  PLOS ONE 7, e47072 PubMed abstract
• Oni, T; Tsekela, R; Kwaza, B; Manjezi, L; Bangani, N; Wilkinson, KA; Coetzee, D and Wilkinson, RJ (2012)
  A recent HIV diagnosis is associated with non-completion of isoniazid preventive therapy in an HIV-infected cohort in Cape Town.
  PLOS ONE 7, e52489 PubMed abstract
• Pepper, DJ; Marais, S; Bhaijee, F; Wilkinson, RJ; De Azevedo, V and Meintjes, G (2012)
  Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
  PLOS ONE 7, e37634 PubMed abstract
• Rangaka, MX; Gideon, HP; Wilkinson, KA; Pai, M; Mwansa-Kambafilwe, J; Maartens, G; Glynn, JR; Boulle, A; Fielding, K; Goliath, R; Titus, R; Mathee, S and Wilkinson, RJ (2012)
  No discriminatory value of interferon release added to smear negative HIV-tuberculosis algorithms.
  European Respiratory Journal 39, 163-171 PubMed abstract
• Rangaka, MX; Gideon, HP; Wilkinson, KA; Pai, M; Mwansa-Kambafwile, J; Maartens, G; Glynn, JR; Boulle, A; Fielding, K; Goliath, R; Titus, R; Mathee, S and Wilkinson, RJ (2012)
  Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms.
  European Respiratory Journal 39, 163-171 PubMed abstract
• Rangaka, MX; Wilkinson, KA; Glynn, JR; Ling, D; Menzies, D; Mwansa-Kambafwile, J; Fielding, K; Wilkinson, RJ and Pai, M (2012)
  Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis.
  Lancet Infectious Diseases 12, 45-55 PubMed abstract
• Rangaka, MX; Wilkinson, RJ; Glynn, JR; Boulle, A; van Cutsem, G; Goliath, R; Mathee, S and Maartens, G (2012)
  Effect of antiretroviral therapy on the diagnostic accuracy of symptom screening for intensified tuberculosis case finding in a South African HIV clinic.
  Clinical Infectious Diseases 55, 1698-1706 PubMed abstract
• Robertson, BD; Altmann, D; Barry, C; Bishai, B; Cole, S; Dick, T; Duncan, K; Dye, C; Ehrt, S; Esmail, H; Flynn, J; Hafner, R; Handley, G; Hanekom, W; van Helden, P; Kaplan, G; Kaufmann, SHE; Kim, P; Lienhardt, C; Mizrahi, V; Rubin, E; Schnappinger, D; Sherman, D; Thole, J; Vandal, O; Walzl, G; Warner, D; Wilkinson, R and Young, D (2012)
  Detection and treatment of subclinical tuberculosis.
  Tuberculosis 92, 447-452 PubMed abstract
• Sarkar, R; Lenders, L; Wilkinson, KA; Wilkinson, RJ and Nicol, MP (2012)
  Modern lineages of Mycobacterium tuberculosis exhibit lineage-specific patterns of growth and cytokine induction in human monocyte-derived macrophages.
  PLOS ONE 7, e43170 PubMed abstract
• Schutz, C; Ismail, Z; Proxenos, CJ; Marais, S; Burton, R; Kenyon, C; Maartens, G; Wilkinson, RJ and Meintjes, G (2012)
  Burden of antituberculosis and antiretroviral drug-induced liver injury at a secondary hospital in South Africa.
  South African Medical Journal 102, 506-511 PubMed abstract
• Skolimowska, KH; Rangaka, MX; Meintjes, G; Pepper, DJ; Seldon, R; Matthews, K; Wilkinson, RJ and Wilkinson, KA (2012)
  Altered ratio of IFN-γ/IL-10 in patients with drug resistant Mycobacterium tuberculosis and HIV- tuberculosis Immune Reconstitution Inflammatory Syndrome.
  PLOS ONE 7, e46481 PubMed abstract
• Vordermeier, HM; Hewinson, RG; Wilkinson, RJ; Wilkinson, KA; Gideon, HP; Young, DB and Sampson, SL (2012)
  Conserved immune recognition hierarchy of mycobacterial PE/PPE proteins during infection in natural hosts.
  PLOS ONE 7, e40890 PubMed abstract
• Walker, NF; Clark, SO; Oni, T; Andreu, N; Tezera, L; Singh, S; Saraiva, L; Pedersen, B; Kelly, DL; Tree, JA; D'Armiento, JM; Meintjes, G; Mauri, FA; Williams, A; Wilkinson, RJ; Friedland, JS and Elkington, PT (2012)
  Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases.
  American Journal of Respiratory and Critical Care Medicine 185, 989-997 PubMed abstract
• Wilkinson, KA; Meintjes, G; Seldon, R; Goliath, R and Wilkinson, RJ (2012)
  Immunological characterisation of an unmasking TB-IRIS case.
  South African Medical Journal 102, 512-517 PubMed abstract
• Wilkinson, KA; Torok, ME; Schwander, S and Meintjes, G (2012)
  HIV-associated tuberculosis 2012.
  Clinical and Developmental Immunology 2012, 950964 PubMed abstract
• Wilkinson, RJ (2012)
  Human genetic susceptibility to tuberculosis: time for a bottom-up approach?
  Journal of Infectious Diseases 205, 525-527
• Dodd, LE and Wilkinson, RJ (2011)
  Isoniazid preventive therapy in HIV infection.
  Lancet 377, 1548-1550 PubMed abstract
• Esmail, H; Barry, CE, 3rd and Wilkinson, RJ (2011)
  Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies.
  Drug Discovery Today 17, 514-521 PubMed abstract
• Jones, GJ; Pirson, C; Gideon, HP; Wilkinson, KA; Sherman, DR; Wilkinson, RJ; Hewinson, RG and Vordermeier, HM (2011)
  Immune responses to the Enduring Hypoxic Response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology.
  PLOS ONE 6, e21371 PubMed abstract
• Marais, S; Pepper, DJ; Schutz, C; Wilkinson, RJ and Meintjes, G (2011)
  Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting.
  PLOS ONE 6, e20077 PubMed abstract
• Martineau, AR; Nhamoyebonde, S; Oni, T; Rangaka, MX; Marais, S; Bangani, N; Tsekela, R; Bashe, L; de Azevedo, V; Caldwell, J; Venton, TR; Timms, PM; Wilkinson, KA and Wilkinson, RJ (2011)
  Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa.
  Proceedings of the National Academy of Sciences of the United States of America 1058, 19013-19017 PubMed abstract
• Martineau, AR; Timms, PM; Bothamley, GH; Hanifa, Y; Islam, K; Claxton, AP; Packe, GE; Moore-Gillon, JC; Darmalingam, M; Davidson, RN; Milburn, HJ; Baker, LV; Barker, RD; Woodward, NJ; Venton, TR; Barnes, KE; Mullett, CJ; Coussens, AK; Rutterford, CM; Mein, CA; Davies, GR; Wilkinson, RJ; Nikolayevskyy, V; Drobniewski, FA; Eldridge, SM and Griffiths, CJ (2011)
  High-dose vitamin D₃ during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial.
  Lancet 377, 242-250 PubMed abstract
• Matthews, K; Ntsekhe, M; Syed, F; Scriba, T; Russell, J; Tibazarwa, K; Deffur, A; Hanekom, W; Mayosi, BM; Wilkinson, RJ and Wilkinson, KA (2011)
  HIV-1 infection alters CD4⁺ memory T cell phenotype at the site of disease in extrapulmonary tuberculosis.
  European Journal of Immunology 42, 147-157 PubMed abstract
• Matthews, K; Wilkinson, KA; Kalsdorf, B; Roberts, T; Diacon, A; Walzl, G; Wolske, J; Ntsekhe, M; Syed, F; Russell, J; Mayosi, BM; Dawson, R; Dheda, K; Wilkinson, RJ; Hanekom, WA and Scriba, TJ (2011)
  Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis.
  Tuberculosis 91, 587-593 PubMed abstract
• McNab, FW; Berry, MPR; Graham, CM; Bloch, SAA; Oni, T; Wilkinson, KA; Wilkinson, RJ; Kon, OM; Banchereau, J; Chaussabel, D and O'Garra, A (2011)
  Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis.
  European Journal of Immunology 41, 1941-1947 PubMed abstract
• Oni, T; Burke, R; Tsekela, R; Bangani, N; Seldon, R; Gideon, HP; Wood, K; Wilkinson, KA; Ottenhoff, THM and Wilkinson, RJ (2011)
  High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening.
  Thorax 66, 669-673 PubMed abstract
• Pepper, DJ; Marais, S; Wilkinson, RJ; Bhaijee, F; De Azevedo, V and Meintjes, G (2011)
  Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa.
  PLOS ONE 6, e1984 PubMed abstract
• Tadokera, R; Meintjes, G; Skolimowska, KH; Wilkinson, KA; Matthews, K; Seldon, R; Chegou, NN; Maartens, G; Rangaka, MX; Rebe, K; Walzl, G and Wilkinson, RJ (2011)
  Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
  European Respiratory Journal 37, 1248-1259 PubMed abstract
• Asselman, V; Thienemann, F; Pepper, DJ; Boulle, A; Wilkinson, RJ; Meintjes, G and Marais, S (2010)
  Central nervous system disorders after starting antiretroviral therapy in South Africa.
  AIDS 24, 2871-2876 PubMed abstract
• Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2010)
  Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes: authors' reply.
  Nature Reviews Microbiology 8, 242
• Berry, MPR; Graham, CM; McNab, FW; Xu, Z; Bloch, SAA; Oni, T; Wilkinson, KA; Banchereau, R; Skinner, J; Wilkinson, RJ; Quinn, C; Blankenship, D; Dhawan, R; Cush, JJ; Mejias, A; Ramilo, O; Kon, OM; Pascual, V; Banchereau, J; Chaussabel, D and O'Garra, A (2010)
  An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.
  Nature 466, 973-977 PubMed abstract
• Bhaijee, F; Wainwright, H; Meintjes, G; Wilkinson, RJ; Todd, G; de Vries, E and Pepper, DJ (2010)
  Warfarin-induced skin necrosis in HIV-1-infected patients with tuberculosis and venous thrombosis.
  South African Medical Journal 100, 372-377 PubMed abstract
• Chatterjee, A; D'Souza, D; Vira, T; Bamne, A; Ambe, GT; Nicol, MP; Wilkinson, RJ and Mistry, N (2010)
  Strains of Mycobacterium tuberculosis from Western Maharashtra, India exhibit a high degree of diversity and strain-specific associations with drug resistance, cavitary disease and treatment failure.
  Journal of Clinical Microbiology 48, 3593-3599 PubMed abstract
• Chun, RF; Lauridsen, AL; Suon, L; Zella, LA; Pike, JW; Modlin, RL; Martineau, AR; Wilkinson, RJ; Adams, J and Hewison, M (2010)
  Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D.
  Journal of Clinical Endocrinology and Metabolism 95, 3368-3376 PubMed abstract
• Connell, TG; Davies, MA; Johannisen, C; Wood, K; Pienaar, S; Wilkinson, KA; Wilkinson, RJ; Zar, HJ; Beatty, D; Nicol, MP; Curtis, N and Eley, B (2010)
  Reversion and conversion of Mycobacterium tuberculosis IFN-γ ELISpot results during anti-tuberculous treatment in HIV-infected children.
  BMC Infectious Diseases 10, 138 PubMed abstract
• Gideon, HP; Wilkinson, KA; Rustad, TR; Oni, T; Guio, H; Kozak, RA; Sherman, DR; Meintjes, G; Behr, MA; Vordermeier, HM; Young, DB and Wilkinson, RJ (2010)
  Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
  PLOS Pathogens 6, e1001237 PubMed abstract
• Lange, C and Wilkinson, RJ (2010)
  Vitamin D and active tuberculosis: a futile quest?
  American Journal of Respiratory and Critical Care Medicine 181, 95
• Lawn, SD and Wilkinson, RJ (2010)
  Primate model to study reactivation of TB associated with retroviral infection.
  Future Virology 5, 391-395
• Lawn, SD; Wood, R and Wilkinson, RJ (2010)
  Changing concepts of "latent tuberculosis infection" in patients living with HIV infection.
  Clinical & Developmental Immunology 2011, 980594 PubMed abstract
• Marais, S; Scholtz, P; Pepper, DJ; Meintjes, G; Wilkinson, RJ and Candy, S (2010)
  Neuroradiological features of the tuberculosis-associated immune reconstitution inflammatory syndrome.
  International Journal of Tuberculosis and Lung Disease 14, 188-196 PubMed abstract
• Marais, S; Thwaites, G; Schoeman, JF; Török, ME; Misra, UK; Prasad, K; Donald, PR; Wilkinson, RJ and Marais, BJ (2010)
  Tuberculous meningitis: a uniform case definition for use in clinical research.
  Lancet Infectious Diseases 10, 803-812 PubMed abstract
• Martineau, AR; Leandro, ACCS; Anderson, ST; Newton, SM; Wilkinson, KA; Nicol, MP; Pienaar, SM; Skolimowska, KH; Rocha, MA; Rolla, VC; Levin, M; Davidson, RN; Bremner, SA; Griffiths, CJ; Eley, BS; Bonecini-Almeida, MG and Wilkinson, RJ (2010)
  Association between Gc genotype and susceptibility to TB is dependent on vitamin D status.
  European Respiratory Journal 35, 1106-1112 PubMed abstract
• Meintjes, G and Wilkinson, RJ (2010)
  Optimum timing of antiretroviral therapy for HIV-infected patients with concurrent serious opportunistic infections.
  Clinical Infectious Diseases 50, 1539-1541 PubMed abstract
• Meintjes, G and Wilkinson, RJ (2010)
  Undiagnosed active tuberculosis in HIV-infected patients commencing antiretroviral therapy.
  Clinical Infectious Diseases 51, 830-832 PubMed abstract
• Meintjes, G; Wilkinson, RJ; Morroni, C; Pepper, DJ; Rebe, K; Rangaka, MX; Oni, T and Maartens, G (2010)
  Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome.
  AIDS 24, 2381-2390 PubMed abstract
• Oni, T; Patel, J; Gideon, HP; Seldon, R; Wood, K; Hlombe, Y; Wilkinson, KA; Rangaka, MX; Mendelson, M and Wilkinson, RJ (2010)
  Enhanced diagnosis of HIV-1 associated tuberculosis by relating T-SPOT.TB and CD4 counts.
  European Respiratory Journal 36, 594-600 PubMed abstract
• Pepper, DJ; Marais, S; Wilkinson, RJ; Bhaijee, F; Maartens, G; McIlleron, H; De Azevedo, V; Cox, H; McDermid, C; Sokhela, S; Patel, J and Meintjes, G (2010)
  Clinical deterioration during anti-tuberculosis treatment in Africa: Incidence, causes and risk factors.
  BMC Infectious Diseases 10, 83 PubMed abstract
• Schutz, C; Meintjes, G; Almajid, F; Wilkinson, RJ and Pozniak, A (2010)
  Clinical management of tuberculosis and HIV-1 co-infection.
  European Respiratory Journal 36, 1460-1481 PubMed abstract
• Tena-Coki, NG; Scriba, TJ; Peteni, N; Eley, B; Wilkinson, RJ; Andersen, P; Hanekom, WA and Kampmann, B (2010)
  CD4 and CD8 T cell responses to mycobacterial antigens in African children.
  American Journal of Respiratory and Critical Care Medicine 182 , 120-129 PubMed abstract
• Wilkinson, KA and Wilkinson, RJ (2010)
  Polyfunctional T cells in human tuberculosis.
  European Journal of Immunology 40, 2139-2142 PubMed abstract
• Wood, R; Liang, H; Wu, H; Middelkoop, K; Oni, T; Rangaka, MX; Wilkinson, RJ; Bekker, L-G and Lawn, SD (2010)
  Changing prevalence of tuberculosis infection with increasing age in high-burden townships in South Africa.
  International Journal of Tuberculosis and Lung Disease 14, 406-412 PubMed abstract
• Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2009)
  The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
  Nature Reviews Microbiology 7, 845-855 PubMed abstract
• Berry, MPR; Graham, CM; Bloch, SJ; Oni, T; Wilkinson, KA; Wilkinson, RJ; Kon, OM; Banchereau, J; Chaussabel, D and O'Garra, A (2009)
  Systems biology approaches characterise the host response to tuberculosis.
  Thorax 64, A10-A13
• Davies, MA; Connell, T; Johannisen, C; Wood, K; Pienaar, S; Wilkinson, KA; Wilkinson, RJ; Zar, HJ; Eley, B; Beatty, D; Curtis, N and Nicol, MP (2009)
  Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.
  AIDS 23, 961-969 PubMed abstract
• Dsouza, DTB; Mistry, NF; Vira, TS; Dholakia, Y; Hoffner, S; Pasvol, G; Nicol, M and Wilkinson, RJ (2009)
  High levels of multidrug resistant tuberculosis in new and treatment-failure patients from the Revised National Tuberculosis Control Programme in an urban metropolis (Mumbai) in Western India.
  BMC Public Health 9, 211 PubMed abstract
• Kalsdorf, B; Scriba, TJ; Wood, K; Day, CL; Dheda, K; Dawson, R; Hanekom, WA; Lange, C and Wilkinson, RJ (2009)
  HIV-1 infection impairs the bronchoalveolar T cell response to mycobacteria.
  American Journal of Respiratory and Critical Care Medicine 180, 1262-1270 PubMed abstract
• Marais, S; Wilkinson, RJ; Pepper, DJ and Meintjes, G (2009)
  Management of patients with the immune reconstitution inflammatory syndrome.
  Current HIV/AIDS reports 6, 162-171 PubMed abstract
• Martineau, AR; Nanzer, AM; Satkunam, KR; Packe, GE; Rainbow, SJ; Maunsell, ZJ; Timms, PM; Venton, TR; Eldridge, SM; Davidson, RN; Wilkinson, RJ and Griffiths, CJ (2009)
  Influence of a single oral dose of vitamin D₂ on serum 25-hydroxyvitamin D concentrations in tuberculosis patients.
  International Journal of Tuberculosis and Lung Disease 13, 119-125 PubMed abstract
• Meintjes, G; Rabie, H; Wilkinson, RJ and Cotton, MF (2009)
  Tuberculosis-associated immune reconstitution inflammatory syndrome and unmasking of tuberculosis by antiretroviral therapy.
  Clinics in Chest Medicine 30, 797-810 PubMed abstract
• Nicol, MP; Davies, M-A; Wood, K; Hatherill, M; Workman, L; Hawkridge, A; Eley, B; Wilkinson, KA; Wilkinson, RJ; Hanekom, WA; Beatty, D and Hussey, G (2009)
  Comparison of T-SPOT.TB assay and tuberculin skin test for the evaluation of young children at high risk for tuberculosis in a community setting.
  Pediatrics 123, 38-43 PubMed abstract
• Pepper, DJ; Marais, S; Maartens, G; Rebe, K; Morroni, C; Rangaka, MX; Oni, T; Wilkinson, RJ and Meintjes, G (2009)
  Neurologic manifestations of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome: a case series.
  Clinical Infectious Diseases 48, E96-E107 PubMed abstract
• Pepper, DJ; Rebe, K; Morroni, C; Wilkinson, RJ and Meintjes, G (2009)
  Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses.
  PLOS ONE 4, e4520 PubMed abstract
• Sarrazin, H; Wilkinson, KA; Andersson, J; Rangaka, MX; Radler, L; van Veen, K; Lange, C and Wilkinson, RJ (2009)
  Association between tuberculin skin test reactivity, the memory CD4 cell subset, and circulating FoxP3-expressing cells in HIV-infected persons.
  Journal of Infectious Diseases 199, 702-710 PubMed abstract
• Schafer, G; Jacobs, M; Wilkinson, RJ and Brown, GD (2009)
  Non-opsonic recognition of Mycobacterium tuberculosis by phagocytes.
  Journal of Innate Immunity 1, 231-243 PubMed abstract
• Wilkinson, KA; Newton, SM; Stewart, GR; Martineau, AR; Patel, J; Sullivan, SM; Herrmann, JL; Neyrolles, O; Young, DB and Wilkinson, RJ (2009)
  Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis.
  BMC Microbiology 9, 93 PubMed abstract
• Wilkinson, KA; Seldon, R; Meintjes, G; Rangaka, MX; Hanekom, WA; Maartens, G and Wilkinson, RJ (2009)
  Dissection of regenerating T cell responses against tuberculosis in HIV infected adults sensitized by Mycobacterium tuberculosis.
  American Journal of Respiratory and Critical Care Medicine 180, 674-683 PubMed abstract
• Wilkinson, RJ and Lange, C (2009)
  Vitamin D and tuberculosis: new light on a potent biologic therapy?
  American Journal of Respiratory and Critical Care Medicine 179, 740-742 PubMed abstract
• Young, DB; Gideon, HP and Wilkinson, RJ (2009)
  Eliminating latent tuberculosis.
  Trends in Microbiology 17, 183-188 PubMed abstract
• Chege, GK; Warren, RW; Gey van Pittius, NC; Burgers, WA; Wilkinson, RJ; Shephard, EG and Williamson, A-L (2008)
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