Acting Head of Division - Troy Margrie

The billions of neurons in our brain process information that allows us to perceive the world around us. They are organised into discrete functional networks that interact with one another both locally and over long distances to encode and relay sensory information, lay down memories and generate ideas.

One major aim of the Division of Neurophysiology is, through basic research, to determine how processing of sensory information at the level of synapses, individual neurons and neuronal networks give rise to perception, behaviour and decision-making. By examining the cellular and network processes involved in sensory representation, we want to understand the "how" and "why" of normal brain operation. Answers to these questions will shed light on "what goes wrong" in neurological and cognitive dysfunction. To achieve this goal we use a variety of techniques that range from genetics and single cell recordings in neuronal cultures and brain slices up to in vivo two-photon microscopy, electrophysiology and behaviour.

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