MRC National Institute for Medical Research, London
Science for Health
Mike Blackman Publications
- Collins, CR and Blackman, MJ (2012)
Apicomplexan AMA1 in host cell invasion: a model at the junction?
Cell Host & Microbe 10, 531-533 PubMed abstract - da Cruz, LN; Juliano, MA; Budu, A; Juliano, L; Holder, AA; Blackman, MJ and Garcia, CRS (2012)
Extracellular ATP triggers proteolysis and cytosolic Ca2+ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.
Malaria Journal 11, PubMed abstract - Olivieri, A; Collins, CR; Hackett, F; Withers-Martinez, C; Marshall, J; Flynn, HR; Skehel, JM and Blackman, MJ (2011)
Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies.
PLoS Pathogens 7, e1002448 - Santos, JM; Ferguson, DJP; Blackman, MJ and Soldati-Favre, D (2011)
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.
Science 331, 473-477 PubMed abstract - Silmon de Monerri, NC; Flynn, HR; Campos, MG; Hackett, F; Koussis, K; Withers-Martinez, C; Skehel, JM and Blackman, MJ (2011)
Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease.
Infection and Immunity 79, 1086-1097 PubMed abstract - Child, MA; Epp, C; Bujard, H and Blackman, MJ (2010)
Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth.
Molecular Microbiology 78, 187-202 PubMed abstract - Dvorin, JD; Martyn, DC; Patel, SD; Grimley, JS; Collins, CR; Hopp, CS; Bright, AT; Westenberger, S; Winzeler, E; Blackman, MJ; Baker, DA; Wandless, TJ and Duraisingh, MT (2010)
A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes.
Science 328, 910-912 PubMed abstract - Friedrich, N; Santos, JM; Liu, Y; Palma, AS; Leon, E; Saouros, S; Kiso, M; Blackman, MJ; Matthews, S; Feizi, T and Soldati-Favre, D (2010)
Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by Apicomplexan parasites.
Journal of Biological Chemistry 285, 2064-2076 PubMed abstract - Woehlbier, U; Epp, C; Hackett, F; Blackman, MJ and Bujard, H (2010)
Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion.
Malaria Journal 9, 77 PubMed abstract - Collins, CR; Withers-Martinez, C; Hackett, F and Blackman, MJ (2009)
An inhibitory antibody blocks interactions between components of the malarial invasion machinery.
PLoS Pathogens 5, e1000273 PubMed abstract - Doerig, C; Baker, D; Billker, O; Blackman, MJ; Chitnis, C; Kumar, DS; Heussler, V; Holder, AA; Kocken, C; Krishna, S; Langsley, G; Lasonder, E; Menard, R; Meissner, M; Pradel, G; Ranford-Cartwright, L; Sharma, A; Sharma, P; Tardieux, T; Tatu, U and Alano, P (2009)
Signalling in malaria parasites.
Parasite 16, 169-182 PubMed abstract - Koussis, K; Withers-Martinez, C; Yeoh, S; Child, M; Hackett, F; Knuepfer, E; Juliano, L; Woehlbier, U; Bujard, H and Blackman, MJ (2009)
A multifunctional serine protease primes the malaria parasite for red blood cell invasion.
EMBO Journal 28, 725-735 PubMed abstract - Lazarou, M; Guevara Patiño, JA; Jennings, RM; McIntosh, RS; Shi, J; Howell, S; Cullen, E; Jones, T; Adame-Gallegos, JR; Chappel, JA; McBride, JS; Blackman, MJ; Holder, AA and Pleass, RJ (2009)
Inhibition of erythrocyte invasion and Plasmodium falciparum Merozoite Surface Protein 1 processing by human IgG1 and IgG3 antibodies.
Infection and Immunity 77, 5659-5667 PubMed abstract - Wanyiri, JW; Techasintana, P; O'Connor, RM; Blackman, MJ; Kim, K and Ward, HD (2009)
Role of CpSUB1, a subtilisin-like protease in Cryptosporidium parvum infection in vitro.
Eukaryotic Cell 8, 470-477 PubMed abstract - Blackman, MJ (2008)
Malarial proteases and host cell egress: an 'emerging' cascade.
Cellular Microbiology 10, 1925-1934 PubMed abstract - Dowse, TJ; Koussis, K; Blackman, MJ and Soldati-Favre, D (2008)
Roles of proteases during invasion and egress by Plasmodium and Toxoplasma.
In: Molecular Mechanisms of Parasite Invasion. Edited by Burleigh, AB.
New York, Springer, 2008. 121-139. (Subcellular Biochemistry, - Sawmynaden, K; Saouros, S; Friedrich, N; Marchant, J; Simpson, P; Bleijlevens, B; Blackman, MJ; Soldati-Favre, D and Matthews, S (2008)
Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition.
EMBO Reports 9, 1149-1155 PubMed abstract - Withers-Martinez, C; Haire, LF; Hackett, F; Walker, PA; Howell, SA; Smerdon, SJ; Dodson, GG and Blackman, MJ (2008)
Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.
Journal of Molecular Biology 375, 773-781 PubMed abstract - Blumenschein, TMA; Friedrich, N; Childs, RA; Saouros, S; Carpenter, EP; Campanero-Rhodes, MA; Simpson, P; Chai, W; Koutroukides, T; Blackman, MJ; Feizi, T; Soldati-Favre, D and Matthews, S (2007)
Atomic resolution insight into host cell recognition by Toxoplasma gondii.
EMBO Journal 26, 2808-2820 PubMed abstract - Collins, CR; Withers-Martinez, C; Bentley, GA; Batchelor, AH; Thomas, AW and Blackman, MJ (2007)
Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.
Journal of Biological Chemistry 282, 7431-7441 PubMed abstract - Yeoh, S; O'Donnell, RA; Koussis, K; Dluzewski, AR; Ansell, KH; Osborne, SA; Hackett, F; Withers-Martinez, C; Mitchell, GH; Bannister, LH; Bryans, JS; Kettleborough, CA and Blackman, MJ (2007)
Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.
Cell 131, 1072-1083 PubMed abstract - Montero, E; Gonzalez, LM; Rodriguez, M; Oksov, Y; Blackman, MJ and Lobo, CA (2006)
A conserved subtilisin protease identified in Babesia divergens merozoites.
Journal of Biological Chemistry 281, 35717-35726 PubMed abstract - O'Donnell, RA; Hackett, F; Howell, SA; Treeck, M; Struck, N; Krnajski, Z; Withers-Martinez, C; Gilberger, TW and Blackman, MJ (2006)
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.
Journal of Cell Biology 174, 1023-1033 PubMed abstract
[Page last updated 1 May 2012]
© MRC National Institute for Medical Research
The Ridgeway, Mill Hill, London NW7 1AA
Top of page