Science for Health
bottom tail (wildtype) shows normal circulatory flow around the tail muscle, absent in dst tail (top)
dst embryos (top) show an enlarged heart, but heartbeat is relatively normal compared to wildtype (bottom).
dst embryos (left) show enlarged heart as well as a paucity of erythrocytes compared to wildtype (right)
mrs lot tadpoles are paralyzed, and do not respond to tactile stimulus such as being touched with forceps.
petrified embryos fail to respond to tactile stimulus, such as being touched with forceps. Touching a wildtype outcrossed sibling embryo (top) elicits an escape response.
petrified tadpole (bottom) shows no heartbeat compared to wildtype embryo (top).
Wildtype embryo (top) shows beating heart; muzak embryo (bottom) shows no heartbeat.
at N&F stage 37, cruella heartbeat is very weak.
at N&F stage 37, wildtype embryos display a robust heartbeat.
Later stages show a small, abnormal, albeit beating heart, as well as substantial edema.
© MRC National Institute for Medical Research
The Ridgeway, Mill Hill, London NW7 1AA