MRC National Institute for Medical Research, London
Science for Health
Luiz Pedro de Carvalho Publications
- Goldstone, DC; Ennis-Adeniran, V; Hedden, JJ; Groom, HCT; Rice, GI; Christodoulou, E; Walker, PA; Kelly, G; Haire, LF; Yap, MW; de Carvalho, LP; Stoye, JP; Crow, YJ; Taylor, IA and Webb, M (2011)
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
Nature 480, 379-382 PubMed abstract - de Carvalho, LPS; Fischer, SM; Marrero, J; Nathan, C; Ehrt, S and Rhee, KY (2010)
Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.
Chemistry & Biology 17, 1122-1131 PubMed abstract - de Carvalho, LPS; Zhao, H; Dickinson, CE; Arango, NM; Lima, CD; Fischer, SM; Ouerfelli, O; Nathan, C and Rhee, KY (2010)
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.
Chemistry & Biology 17, 323-332 PubMed abstract - Zhao, H; de Carvalho, LPS; Nathan, C and Ouerfelli, O (2010)
A protecting group-free synthesis of deazathiamine: a step toward inhibitor design.
Bioorganic & Medicinal Chemistry Letters 20, 6472-6474 PubMed abstract - de Carvalho, LPS; Frantom, PA; Argyrou, A and Blanchard, JS (2009)
Kinetic evidence for interdomain communication in the allosteric regulation of α-isopropylmalate synthase from Mycobacterium tuberculosis.
Biochemistry 48, 1996-2004 PubMed abstract - de Carvalho, LPS; Lin, G; Jiang, X and Nathan, C (2009)
Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance.
Journal of Medicinal Chemistry 52, 5789-5792 PubMed abstract - Lee, WL; Gold, B; Darby, C; Brot, N; Jiang, X; De Carvalho, LPS; Wellner, D; St. John, G; Jacobs Jr, WR and Nathan, C (2009)
Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite.
Molecular Microbiology 71, 583-593 PubMed abstract - Lin, G; Li, D; de Carvalho, LPS; Deng, H; Tao, H; Vogt, G; Wu, K; Schneider, J; Chidawanyika, T; Warren, JD; Li, H and Nathan, C (2009)
Inhibitors selective for mycobacterial versus human proteasomes.
Nature 461, 621-626 PubMed abstract - de Carvalho, LPS and Blanchard, JS (2006)
Kinetic analysis of the effects of monovalent cations and divalent metals on the activity of Mycobacterium tuberculosis α-isopropylmalate synthase.
Archives of Biochemistry and Biophysics 451, 141-148 PubMed abstract - de Carvalho, LPS and Blanchard, JS (2006)
Kinetic and chemical mechanism of α-isopropylmalate synthase from Mycobacterium tuberculosis.
Biochemistry 45, 8988-8999 PubMed abstract - Silva, RG; de Carvalho, LPS; Blanchard, JS; Santos, DS and Basso, LA (2006)
Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein (ACP) reductase: kinetic and chemical mechanisms.
Biochemistry 45, 13064-13073 PubMed abstract - Yu, M; de Carvalho, LPS; Sun, G and Blanchard, JS (2006)
Activity-based substrate profiling for Gcn5-related N-acetyltransferases: the use of chloroacetyl-coenzyme A to identify protein substrates.
Journal of the American Chemical Society 128, 15356-15357 PubMed abstract
[Page last updated 1 May 2012]
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