MRC National Institute for Medical Research, London
Science for Health
James Briscoe Biography
James Briscoe is a group leader in the Division of Developmental Neurobiology. He obtained a B.Sc. in Microbiology and Virology from the University of Warwick, UK. Following his Ph.D. research in Ian Kerr's laboratory at the Imperial Cancer Research Fund, London (now Cancer Research UK), he undertook postdoctoral training at Columbia University, New York, USA, with Thomas Jessell first as a Human Frontiers Science Program Fellow then as a Howard Hughes Medical Institute Fellow.
In 2000 he moved to NIMR to establish his own research group and in 2001 he was elected an EMBO Young Investigator. He was awarded the EMBO Gold Medal in 2008 and elected to EMBO in 2009.
His current research interests include the molecular mechanisms of graded signalling by hedgehog ligands and the specification of cell fate in the vertebrate neural tube. To address these questions his lab uses a range of techniques and model systems including mouse, chick and zebrafish.
Briscoe group
Recent publications
Research projects
- Dynamics of Shh signalling and gene expression
- Coordinating patterning and growth
- Elucidation of the transcriptional network
- Visualising gene expression
- Development of the serotonergic system
Briscoe biography
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