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Douglas Young Publications

Portevin, D; Gagneux, S; Comas, I and Young, D (2011)
Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages.
PLoS Pathogens 7, e1001307 PubMed abstract
Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2010)
Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes: authors' reply.
Nature Reviews Microbiology 8, 242
Arnvig, KB and Young, DB (2009)
Identification of small RNAs in Mycobacterium tuberculosis.
Molecular Microbiology 73, 397-408 PubMed abstract
Barry, CE, 3rd; Boshoff, HI; Dartois, V; Dick, T; Ehrt, S; Flynn, J; Schnappinger, D; Wilkinson, RJ and Young, D (2009)
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
Nature Reviews Microbiology 7, 845-855 PubMed abstract
Wilkinson, KA; Newton, SM; Stewart, GR; Martineau, AR; Patel, J; Sullivan, SM; Herrmann, JL; Neyrolles, O; Young, DB and Wilkinson, RJ (2009)
Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis.
BMC Microbiology 9, 93 PubMed abstract
Young, D (2009)
Animal models of tuberculosis.
European Journal of Immunology 39, 2011-2014 PubMed abstract
Young, DB; Gideon, HP and Wilkinson, RJ (2009)
Eliminating latent tuberculosis.
Trends in Microbiology 17, 183-188 PubMed abstract
Ameni, G; Aseffa, A; Sirak, A; Engers, H; Young, DB; Hewinson, RG; Vordermeier, MH and Gordon, SV (2007)
Effect of skin testing and segregation on the prevalence of bovine tuberculosis, and molecular typing of Mycobacterium bovis, in Ethiopia.
Veterinary Record 161, 782-786 PubMed abstract
Ameni, G; Aseffa, A; Engers, H; Young, D; Hewinson, G and Vordermeier, M (2006)
Cattle husbandry in Ethiopia is a predominant factor affecting the pathology of bovine tuberculosis and gamma interferon responses to mycobacterial antigens.
Clinical and Vaccine Immunology 13, 1030-1036 PubMed abstract
Humphreys, IR; Stewart, GR; Turner, DJ; Patel, J; Karamanou, D; Snelgrove, RJ and Young, DB (2006)
A role for dendritic cells in the dissemination of mycobacterial infection.
Microbes and Infection 8, 1339-1346 PubMed abstract
Louw, GE; Warren, RM; Donald, PR; Murray, MB; Bosman, M; Van Helden, PD; Young, DB and Victor, TC (2006)
Frequency and implications of pyrazinamide resistance in managing previously treated tuberculosis patients.
International Journal of Tuberculosis and Lung Disease 10, 802-807 PubMed abstract
Stadthagen, G; Jackson, M; Charles, P; Boudou, F; Barilone, N; Huerre, M; Constant, P; Liav, A; Bottova, I; Nigou, J; Brando, T; Puzo, G; Daffe, M; Benjamin, P; Coade, S; Buxton, RS; Tascon, RE; Rae, A; Robertson, BD; Lowrie, DB; Young, DB; Gicquel, B and Griffin, R (2006)
Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives.
Microbes and Infection 8, 2245-2253 PubMed abstract
Stumpf, MP; Robertson, BD; Duncan, K and Young, DB (2006)
Systems biology and its impact on anti-infective drug development.
In: Systems biological approaches in infectious diseases. Edited by Boshoff, HI and Barry, CE.
Basel, Birkhauser Verlag, 2006. 1-20. (Progress in Drug Research, 64).
Young, DB (2006)
Systems biology could help us harness useful microbes.
Nature 442, 627 PubMed abstract
Young, DB and Dye, C (2006)
The development and impact of tuberculosis vaccines.
Cell 124, 683-687 PubMed abstract