MRC National Institute for Medical Research, London

• Berriman, JA and Rosenthal, PB (2012)
  Paraxial charge compensator for electron cryomicroscopy.
  Ultramicroscopy 116, 106-114 PubMed abstract
• Bianco, PR and Webb, MR (2012)
  Helicase unwinding: active or merely perfect?
  Journal of Molecular Biology [Epub ahead of print] PubMed abstract
• Galiano, M; Johnson, BF; Myers, R; Ellis, J; Daniels, R and Zambon, M (2012)
  Fatal cases of influenza A(H3N2) in children: insights from whole genome sequence analysis.
  PLoS ONE 7, e33166 PubMed abstract
• Mastelic, B; Freitas do Rosario, AP; Veldhoen, M; Renauld, J-C; Jarra, W; Sponaas, A-M; Roetynck, S; Stockinger, B and Langhorne, J (2012)
  IL-22 protects against liver pathology and lethality of an experimental blood-stage malaria infection.
  Frontiers in Immunology 3, [Epub ahead of print] PubMed abstract
• Stoye, JP (2012)
  Studies of endogenous retroviruses reveal a continuing evolutionary saga.
  Nature Reviews Microbiology [Epub ahead of print] PubMed abstract

View only publications for 21 May 2012

• Bell, AS; Mills, JE; Williams, GP; Brannigan, JA; Wilkinson, AJ; Parkinson, T; Leatherbarrow, RJ; Tate, EW; Holder, AA and Smith, DF (2012)
  Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs.
  PLoS Neglected Tropical Diseases 6, e1625 PubMed abstract
• Freitas do Rosario, AP and Langhorne, J (2012)
  T cell-derived IL-10 and its impact on the regulation of host responses during malaria.
  International Journal for Parasitology [Epub ahead of print] PubMed abstract
• Pacary, E; Martynoga, B and Guillemot, F (2012)
  Crucial first steps: the transcriptional control of neuron delamination.
  Neuron 74, 209-11 PubMed abstract
• Tan, CL; Gunaratne, J; Lai, D; Carthagena, L; Wang, Q; Xue, YZ; Quek, LS; Doorbar, J; Bachelerie, F; Thierry, F and Bellanger, S (2012)
  HPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation.
  Virology [Epub ahead of print] PubMed abstract
• Virgo, N; Fernando, C; Bigge, B and Husbands, P (2012)
  Evolvable physical self-replicators.
  Artificial Life 18, 129-142
• Withers-Martinez, C; Suarez, C; Fulle, S; Kher, S; Penzo, M; Ebejer, J-P; Koussis, K; Hackett, F; Jirgensons, A; Finn, P and Blackman, MJ (2012)
  Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.
  International Journal for Parasitology [Epub ahead of print] PubMed abstract

View only publications for 14 May 2012

• Hollingworth, D; Candel, AM; Nicastro, G; Martin, SR; Briata, P; Gherzi, R and Ramos, A (2012)
  KH domains with impaired nucleic acid binding as a tool for functional analysis.
  Nucleic Acids Research [Epub ahead of print] PubMed abstract
• Liberles, DA; Teichmann, SA; Bahar, I; Bastolla, U; Bloom, J; Bornberg-Bauer, E; Colwell, LJ; de Koning, APJ; Dokholyan, NV; Echave, J; Elofsson, A; Gerloff, DL; Goldstein, RA; Grahnen, JA; Holder, MT; Lakner, C; Lartillot, N; Lovell, SC; Naylor, G; Perica, T; Pollock, DD; Pupko, T; Regan, L; Roger, A; Rubinstein, N; Shakhnovich, E; Sjölander, K; Sunyaev, S; Teufel, AI; Thorne, JL; Thornton, JW; Weinreich, DM and Whelan, S (2012)
  The interface of protein structure, protein biophysics, and molecular evolution.
  Protein Science [Epub ahead of print] PubMed abstract
• Pearson, C; Silva, A and Seddon, B (2012)
  Exogenous amino acids Are essential for interleukin-7 induced CD8 T cell growth.
  PLoS ONE 7, e33998 PubMed abstract
• Pollock, DD; Thiltgen, G and Goldstein, RA (2012)
  Amino acid coevolution induces an evolutionary Stokes shift.
  Proceedings of the National Academy of Sciences of the United States of America [Epub ahead of print]
• Stieglitz, B; Haire, LF; Dikic, I and Rittinger, K (2012)
  Structural analysis of SHARPIN, a subunit of a large multi-protein E3 ubiquitin ligase, reveals a novel dimerization function for the pleckstrin homology superfold.
  Journal of Biological Chemistry [Epub ahead of print]
• Tuomela, S; Salo, V; Tripathi, SK; Chen, Z; Laurila, K; Gupta, B; äijö, T; Oikari, L; Stockinger, B; Lähdesmäki, H and Lahesmaa, R (2012)
  Identification of early gene expression changes during human Th17 cell differentiation.
  Blood [Epub ahead of print] PubMed abstract
• Walker, NF; Clark, SO; Oni, T; Andreu, N; Tezera, L; Singh, S; Saraiva, L; Pedersen, B; Kelly, DL; Tree, JA; D'Armiento, JM; Meintjes, G; Mauri, FA; Williams, A; Wilkinson, RJ; Friedland, JS and Elkington, PT (2012)
  Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases.
  American Journal of Respiratory and Critical Care Medicine 185, 989-997
• Wojtasz, L; Cloutier, JM; Baumann, M; Daniel, K; Varga, J; Fu, J; Anastassiadis, K; Stewart, AF; Reményi, A; Turner, JMA and Tóth, A (2012)
  Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.
  Genes & Development 26, 958-973

View only publications for 07 May 2012

• Ampofo, WK; Baylor, N; Cobey, S; Cox, NJ; Daves, S; Edwards, S; Ferguson, N; Grohmann, G; Hay, A; Katz, J; Kullabutr, K; Lambert, L; Levandowski, R; Mishra, AC; Monto, A; Siqueira, M; Tashiro, M; Waddell, AL; Wairagkar, N; Wood, J; Zambon, M and Zhang, W (2012)
  Improving influenza vaccine virus selection. Report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010.
  Influenza and Other Respiratory Viruses 6, 14-152 PubMed abstract
• Nenasheva, TA; Carter, T and Mashanov, GI (2012)
  Automatic tracking of individual migrating cells using low-magnification dark-field microscopy.
  Journal of Microscopy 246, 83-88 PubMed abstract
• Rees, M; Gorba, C; de Chiara, C; Bui, TTT; Garcia-Maya, M; Drake, Alex F; Okazawa, H; Pastore, A; Svergun, D and Chen, Yu W (2012)
  Solution model of the intrinsically disordered polyglutamine tract-binding protein-1.
  Biophysical Journal 102, 1608-1616 PubMed abstract
• Salamat, MK; Moudjou, M; Chapuis, J; Herzog, L; Jaumain, E; Béringue, V; Rezaei, H; Pastore, A; Laude, H and Dron, M (2012)
  The integrity of helix 2 helix 3 domain of PrP protein is not mandatory for prion replication.
  Journal of Biological Chemistry [Epub ahead of print] PubMed abstract
• Smollett, KL; Smith, KM; Kahramanoglou, C; Arnvig, KB; Buxton, RS and Davis, EO (2012)
  Global analysis of the regulon of the transcriptional repressor LexA, a key component of the SOS response in Mycobacterium tuberculosis.
  Journal of Biological Chemistry [Epub ahead of print] PubMed abstract
• Thorpe, PH; Dittmar, JC and Rothstein, R (2012)
  ScreenTroll: a searchable database to compare genome-wide yeast screens.
  Database [Epub ahead of print] PubMed abstract

View only publications for 30 April 2012

View only publications for 23 April 2012

• Arbore, C; Lewis, LM and Webb, MR (2012)
  The kinetic mechanism of initiation by RepD as part of asymmetric, rolling circle plasmid unwinding.
  Biochemistry [Epub ahead of print] PubMed abstract
• Bentley, SD; Comas, I; Bryant, JM; Walker, D; Smith, NH; Harris, SR; Thurston, S; Gagneux, S; Wood, J; Antonio, M; Quail, MA; Gehre, F; Adegbola, RA; Parkhill, J and de Jong, BC (2012)
  The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex.
  PLoS Neglected Tropical Diseases 6, e1552
• Chapman, TM; Bouloc, N; Buxton, RS; Chugh, J; Lougheed, KEA; Osborne, SA; Saxty, B; Smerdon, SJ; Taylor, DL and Whalley, D (2012)
  Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis.
  Bioorganic & Medicinal Chemistry Letters [Epub ahead of print] PubMed abstract
• Evans, AL; Faial, T; Gilchrist, MJ; Down, T; Vallier, L; Pedersen, RA; Wardle, FC and Smith, JC (2012)
  Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells.
  PLoS ONE 7, e33346 PubMed abstract
• Fridh, V and Rittinger, K (2012)
  The tandem CARDs of NOD2: intramolecular interactions and recognition of RIP2.
  PLoS ONE 7, e34375 PubMed abstract
• Groom, HCT; Warren, AY; Neal, DE and Bishop, KN (2012)
  No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses.
  PLoS ONE 7, e34221 PubMed abstract
• Haubert, D; Li, J; Saveliev, A; Calzascia, T; Sutter, E; Metzler, B; Kaiser, D; Tybulewicz, VLJ and Weckbecker, G (2012)
  Vav1 GEF activity is required for T cell mediated allograft rejection.
  Transplant Immunology [Epub ahead of print] PubMed abstract
• Houghton, J; Güthlein, C; Williams, AR; Rodgers, A; Rand, L; Walker, KB; Böttger, EC; Springer, B and Davis, EO (2012)
  An important role for Mycobacterium tuberculosis UvrD1 in pathogenesis and persistence apart from its function in nucleotide excision repair.
  Journal of Bacteriology [Epub ahead of print] PubMed abstract
• Khan, SM; Ali, R; Asi, N and Molloy, JE (2012)
  Active actin gels.
  Communicative & integrative biology 5, 39-42 PubMed abstract
• Lawton, J; Brugat, T; Yam, XY; Reid, A; Boehme, U; Otto, T; Pain, A; Jackson, A; Berriman, M; Cunningham, D; Preiser, P and Langhorne, J (2012)
  Characterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS).
  BMC Genomics 13, [Epub ahead of print] PubMed abstract
• Ridzuan, MAM; Moon, RW; Knuepfer, E; Black, S; Holder, AA and Green, JL (2012)
  Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development.
  PLoS ONE 7, e33845 PubMed abstract
• Stapleton, MR; Smith, LJ; Hunt, DM; Buxton, RS and Green, J (2012)
  Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2.
  Tuberculosis [Epub ahead of print] PubMed abstract
• Temussi, PA and Kwang, WJ (2012)
  New insights into the characteristics of sweet and bitter taste receptors.
  International Review of Cell and Molecular Biology 291, 191-226
• Trent, S; Cassano, T; Bedse, G; Ojarikre, OA; Humby, T and Davies, W (2012)
  Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice.
  Neuropsychopharmacology 37, 1267-1274

View only publications for 16 April 2012

• Gantke, T; Sriskantharajah, S; Sadowski, M and Ley, SC (2012)
  IκB kinase regulation of the TPL-2/ERK MAPK pathway.
  Immunological Reviews 246, 168-182 PubMed abstract
• Goncalves, V; Brannigan, JA; Whalley, D; Ansell, KH; Saxty, B; Holder, AA; Wilkinson, AJ; Tate, EW and Leatherbarrow, RJ (2012)
  Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode.
  Journal of Medicinal Chemistry [Epub ahead of print] PubMed abstract
• Isaacson Wechsler, E; Wang, Q; Roberts, I; Pagliarulo, E; Jackson, D; Untersperger, C; Coleman, N; Griffin, H and Doorbar, J (2012)
  Reconstruction of human papillomavirus-16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.
  Journal of Virology [Epub ahead of print]
• Neary, MT; Hall, AR; Hirst, E; Ong, SB; Mohun, TJ; Hausenloy, DJ and Breckenridge, RA (2012)
  Mitochondrial morphology linked with the metabolic transition of cardiac tissue at birth .
  Cardiovascular Research 93 , S5-8S, Oral abstract presentation 20
• van den Boom, J; Heider, D; Martin, SR; Pastore, A and Mueller, JW (2012)
  3'-Phospho-adenosine-5'-phosphosulphate (PAPS) synthases - naturally fragile enzymes specifically stabilised by nucleotide binding.
  Journal of Biological Chemistry [Epub ahead of print]
• Young, GR; Kassiotis, G and Stoye, JP (2012)
  Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice.
  Retrovirology 9, 23 PubMed abstract

View only publications for 02 April 2012

• Abu-Daya, A; Khokha, MK and Zimmerman, LB (2012)
  The Hitchhiker's guide to Xenopus genetics.
  genesis [Epub ahead of print] PubMed abstract
• Adrover, M; Martorell, G; Martin, SR; Urosev, D; Konarev, PV; Svergun, DI; Daura, X; Temussi, P and Pastore, A (2012)
  The role of hydration in protein stability: comparison of the cold and heat unfolded states of Yfh1.
  Journal of Molecular Biology [Epub ahead of print] PubMed abstract
• Bridwell-Rabb, J; Iannuzzi, C; Pastore, A and Barondeau, DP (2012)
  Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis.
  Biochemistry [Epub ahead of print] PubMed abstract
• Fukuda, T; Pratto, F; Schimenti, JC; Turner, JMA; Camerini-Otero, RD and Höög, C (2012)
  Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis.
  PLoS Genetics 8, e1002485 PubMed abstract
• Gilchrist, MJ (2012)
  From expression cloning to gene modeling: the development of Xenopus gene sequence resources.
  genesis [Epub ahead of print] PubMed abstract
• Gindes, L; Matsui, H; Achiron, R; Mohun, T; Ho, SY and Gardiner, H (2012)
  Comparison of ex-vivo high-resolution episcopic microscopy with in-vivo four-dimensional high-resolution transvaginal sonography of the first-trimester fetal heart.
  Ultrasound in Obstetrics & Gynecology 39, 196-202
• Schuster, M; Treitschke, S; Kilaru, S; Molloy, J; Harmer, NJ and Steinberg, G (2012)
  Myosin-5, kinesin-1 and myosin-17 cooperate in secretion of fungal chitin synthase.
  EMBO Journal 31, 214-227
• Temussi, PA (2012)
  The good taste of peptides.
  Journal of Peptide Science 18, 73-82
• Weiner, B; Gomez, J; Victor, TC; Warren, RM; Sloutsky, A; Plikaytis, BB; Posey, JE; van Helden, PD; Gey van Pittius, NC; Koehrsen, M; Sisk, P; Stolte, C; White, J; Gagneux, S; Birren, B; Hung, D; Murray, M and Galagan, J (2012)
  Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region.
  PLoS ONE 7, e26038 PubMed abstract

View only publications for 05 March 2012

• Groom, HCT and Bishop, KN (2012)
  The tale of xenotropic murine leukemia virus-related virus.
  Journal of General Virology [Epub ahead of print]
• Henderson, R; Sali, A; Baker, ML; Carragher, B; Devkota, B; Downing, KH; Egelman, EH; Feng, Z; Frank, J; Grigorieff, N; Jiang, W; Ludtke, SJ; Medalia, O; Penczek, PA; Rosenthal, PB; Rossmann, MG; Schmid, MF; Schröder, GF; Steven, AC; Stokes, DL; Westbrook, JD; Wriggers, W; Yang, H; Young, J; Berman, HM; Chiu, W; Kleywegt, GJ and Lawson, CL (2012)
  Outcome of the first electron microscopy validation task force meeting.
  Structure 20, 205-214 PubMed abstract
• Yata, K; Lloyd, J; Maslen, S; Bleuyard, J-Y; Skehel, M; Smerdon, SJ and Esashi, F (2012)
  Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair.
  Molecular Cell 45, 371-383 PubMed abstract
• Olivieri, A; Collins, CR; Hackett, F; Withers-Martinez, C; Marshall, J; Flynn, HR; Skehel, JM and Blackman, MJ (2011)
  Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies.
  PLoS Pathogens 7, e1002448
• Taylor, WR and Sadowski, MI (2011)
  Structural constraints on the covariance matrix derived from multiple aligned protein sequences.
  PLoS ONE 6, e28265

View only publications for 27 February 2012

• Burlina, F; Morris, C; Behrendt, R; White, P and Offer, J (2012)
  Simplifying native chemical ligation with an N-acylsulfonamide linker.
  Chemical Communications [Epub ahead of print] PubMed abstract
• Collins, CR and Blackman, MJ (2012)
  Apicomplexan AMA1 in host cell invasion: a model at the junction?
  Cell Host & Microbe 10, 531-533 PubMed abstract
• Comas, I; Borrell, S; Roetzer, A; Rose, G; Malla, B; Kato-Maeda, M; Galagan, J; Niemann, S and Gagneux, S (2012)
  Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.
  Nature Genetics 44, 106-110 PubMed abstract
• Lee, K; Tan, J; Morris, MB; Rizzoti, K; Hughes, J; Cheah, PS; Felquer, F; Liu, X; Piltz, S; Lovell-Badge, R and Thomas, PQ (2012)
  Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice.
  PLoS ONE 7, e29041 PubMed abstract
• Lopes, R; Verhey van Wijk, N; Neves, G and Pachnis, V (2012)
  Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum.
  Proceedings of the National Academy of Sciences [Epub ahead of print]
• Sasselli, V; Pachnis, V and Burns, AJ (2012)
  The enteric nervous system.
  Developmental Biology [Epub ahead of print] PubMed abstract
• Sizarov, A; Lamers, WH; Mohun, TJ; Brown, NA; Anderson, RH and Moorman, AFM (2012)
  Three-dimensional and molecular analysis of the arterial pole of the developing human heart.
  Journal of Anatomy [Epub ahead of print] PubMed abstract
• Snelgrove, RJ; Cornere, MM; Edwards, L; Dagg, B; Keeble, J; Rodgers, A; Lyonga, DE; Stewart, GR; Young, DB; Walker, B and Hussell, T (2012)
  OX40 ligand fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection.
  Journal of Infectious Diseases [Epub ahead of print]
• Tattermusch, S; Skinner, JA; Chaussabel, D; Banchereau, J; Berry, MP; McNab, FW; O'Garra, A; Taylor, GP and Bangham, CRM (2012)
  Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy.
  PLoS Pathogens 8, e1002480 PubMed abstract

View only publications for 13 February 2012

• Guttery, DS; Holder, AA and Tewari, R (2012 )
  Sexual development in Plasmodium: lessons from functional analyses.
  PLoS Pathogens 8, e1002404 PubMed abstract
• Balaskas, N; Ribeiro, A; Panovska, J; Dessaud, E; Sasai, N; Page, Karen M; Briscoe, J and Ribes, V (2012)
  Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.
  Cell 148, 273-284 PubMed abstract
• Devoy, A; Bunton-Stasyshyn, RKA; Tybulewicz, VLJ; Smith, AJH and Fisher, EMC (2012)
  Genomically humanized mice: technologies and promises.
  Nature Reviews Genetics 13, 14-20 PubMed abstract
• Ludbrook, LM; Bernard, P; Bagheri-Fam, S; Ryan, J; Sekido, R; Wilhelm, D; Lovell-Badge, R and Harley, VR (2012)
  Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9).
  Endocrinology 153, [Epub ahead of print]

View only publications for 06 February 2012

• Baena-Lopez, LA; Nojima, H and Vincent, JP (2012)
  Integration of morphogen signalling within the growth regulatory network.
  Current Opinion in Cell Biology 24, [Epub ahead of print] PubMed abstract
• Sheppard, O; Wiseman, FK; Ruparelia, A; Tybulewicz, VLJ and Fisher, EMC (2012)
  Mouse models of aneuploidy.
  Scientific World Journal 2012, [Epub ahead of print] PubMed abstract
• Steinhauser, ML; Bailey, AP; Senyo, SE; Guillermier, C; Perlstein, TS; Gould, AP; Lee, RT and Lechene, CP (2012)
  Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism.
  Nature [Epub ahead of print] PubMed abstract
• Tamuri, AU; dos Reis, M and Goldstein, RA (2012)
  Estimating the distribution of selection coefficients from phylogenetic data using sitewise mutation-selection models.
  Genetics [Epub ahead of print]
• Papayannopoulos, V; Metzler, KD; Hakkim, A and Zychlinsky, A (2010)
  Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps.
  Journal of Cell Biology 191, 677-691 PubMed abstract
• Papayannopoulos, V and Zychlinsky, A (2009)
  NETs: a new strategy for using old weapons.
  Trends in Immunology 30, 513-521 PubMed abstract
• Rivera, GM; Vasilescu, D; Papayannopoulos, V; Lim, WA and Mayer, BJ (2009)
  A reciprocal interdependence between Nck and PI(4,5)P2 promotes localized N-WASp-mediated actin polymerization in living cells.
  Molecular Cell 36, 525-535 PubMed abstract
• Papayannopoulos, V; Co, C; Prehoda, KE; Snapper, S; Taunton, J and Lim, WA (2005)
  A polybasic motif allows N-WASP to act as a sensor of PIP2 density.
  Molecular Cell 17, 181-191 PubMed abstract

View only publications for 30 January 2012

• Hu, H; Voss, J; Zhang, G; Buchy, P; Zuo, T; Wang, L; Wang, F; Zhou, F; Wang, G; Tsai, C; Calder, L; Gamblin, SJ; Zhang, L; Deubel, V; Zhou, B; Skehel, JJ and Zhou, P (2012)
  A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.
  Journal of Virology [Epub ahead of print] PubMed abstract
• Jungmichel, S; Clapperton, JA; Lloyd, J; Hari, FJ; Spycher, C; Pavic, L; Li, J; Haire, LF; Bonalli, M; Larsen, DH; Lukas, C; Lukas, J; Macmillan, D; Nielsen, ML; Stucki, M and Smerdon, SJ (2012)
  The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
  Nucleic Acids Research [Epub ahead of print] PubMed abstract
• Matheu, A; Collado, M; Wise, C; Manterola, L; Cekaite, L; Tye, AJ; Canamero, M; Bujanda, L; Schedl, A; Cheah, KSE; Skotheim, RI; Lothe, RA; Lopez de Munain, A; Briscoe, J; Serrano, M and Lovell-Badge, R (2012)
  Oncogenicity of the developmental transcription factor Sox9.
  Cancer Research [Epub ahead of print]

View only publications for 23 January 2012

• Donaldson, IJ; Amin, S; Hensman, JJ; Kutejova, E; Rattray, M; Lawrence, N; Hayes, A; Ward, CM and Bobola, N (2012)
  Genome-wide occupancy links Hoxa2 to Wnt-β-catenin signaling in mouse embryonic development.
  Nucleic Acids Research [Epub ahead of print]
• Gómez-Gaviro, MV; Scott, CE; Sesay, AK; Matheu, A; Booth, S; Galichet, C and Lovell-Badge, R (2012)
  Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis.
  Proceedings of the National Academy of Sciences [Epub ahead of print] PubMed abstract
• Hodson, DJ; Schaeffer, M; Romano, N; Fontanaud, P; Lafont, C; Birkenstock, J; Molino, F; Christian, H; Lockey, J; Carmignac, D; Fernandez-Fuente, M; Le Tissier, P and Mollard, P (2012)
  Existence of long-lasting experience-dependent plasticity in endocrine cell networks.
  Nature Communications 3, 605 PubMed abstract
• Wilkinson, RJ (2012)
  Human genetic susceptibility to tuberculosis: time for a bottom-up approach?
  Journal of Infectious Diseases [Epub ahead of print]
• Bagheri-Fam, S; Sreenivasan, R; Bernard, P; Knower, KC; Sekido, R; Lovell-Badge, R; Just, W and Harley, VR (2011)
  Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens.
  Chromosome Research [Epub ahead of print] PubMed abstract
• Borgogna, C; Zavattaro, E; De Andrea, M; Griffin, HM; Dell'oste, V; Azzimonti, B; Landini, MM; Peh, WL; Pfister, H; Doorbar, J; Landolfo, S and Gariglio, M (2011)
  Characterization of beta papillomavirus E4 expression in tumours from Epidermodysplasia Verruciformis patients and in experimental models.
  Virology [Epub ahead of print] PubMed abstract
• Matthews, K; Ntsekhe, M; Syed, F; Scriba, T; Russell, J; Tibazarwa, K; Deffur, A; Hanekom, W; Mayosi, BM; Wilkinson, RJ and Wilkinson, KA (2011)
  HIV-1 infection alters CD4⁺ memory T cell phenotype at the site of disease in extrapulmonary tuberculosis.
  European Journal of Immunology 42, 147-157 PubMed abstract

View only publications for 16 January 2012

• Batlle, E and Wilkinson, DG (2012)
  Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis.
  Cold Spring Harbor Perspectives in Biology 4, a008227
• Bond, E; Liang, F; Sandgren, KJ; Smed-Sörensen, A; Bergman, P; Brighenti, S; Adams, WC; Betemariam, SA; Rangaka, MX; Lange, C; Wilkinson, RJ; Andersson, J and Loré, K (2012)
  Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.
  Journal of Investigative Dermatology 132, 114-123 PubMed abstract
• Donaldson, IJ; Amin, S; Hensman, JJ; Kutejova, E; Rattray, M; Lawrence, N; Hayes, A; Ward, CM and Bobola, N (2012)
  Genome-wide occupancy links Hoxa2 to Wnt-β-catenin signaling in mouse embryonic development.
  Nucleic Acids Research [Epub ahead of print]
• Le Dréau, G; Garcia-Campmany, L; Rabadán, MA; Ferronha, T; Tozer, S; Briscoe, J and Marti, E (2012)
  Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord.
  Development 139, 259-268 PubMed abstract
• Li, D; Romain, G; Flamar, A-L; Duluc, D; Dullaers, M; Li, X-H; Zurawski, S; Bosquet, N; Palucka, AK; Le Grand, R; O'Garra, A; Zurawski, G; Banchereau, J and Oh, S (2012)
  Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4⁺ T cells.
  Journal of Experimental Medicine [Epub ahead of print]
• Rangaka, MX; Gideon, HP; Wilkinson, KA; Pai, M; Mwansa-Kambafwile, J; Maartens, G; Glynn, JR; Boulle, A; Fielding, K; Goliath, R; Titus, R; Mathee, S and Wilkinson, RJ (2012)
  Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms.
  European Respiratory Journal 39, 163-171 PubMed abstract
• Bains, I; Brauner, CM; Callard, R; Commenges, D; Hogan, T; Seddon, B; Shuvaev, A; Sinclair, C; Thiebaut, R and Yates, A (2011)
  Revealing unexpected cellular dynamics during T cell homeostasis using mathematical models.
  Immunology 135, 6 Abstract No.54
• Bi, Y; Zeng, N; Chanudet, E; Huang, Y; Hamoudi, RA; Liu, H; Dong, G; Watkins, AJ; Ley, SC; Zhou, L; Chen, R; Zhu, X and Du, MQ (2011)
  A20 inactivation in ocular adnexal MALT lymphoma.
  Haematologica [Epub ahead of print] PubMed abstract
• del Portillo, HA; Ferrer, M; Brugat, T; Martin-Jaular, L; Langhorne, J and Lacerda, MVG (2011)
  The role of the spleen in malaria.
  Cellular Microbiology [Epub ahead of print] PubMed abstract
• Duarte, JH; Hirota, K and Stockinger, B (2011)
  Aryl hydrocarbon receptor regulates skin immune responses.
  Immunology 135, 112 Abstract No.823
• Esmail, H; Barry, CE, 3rd and Wilkinson, RJ (2011)
  Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies.
  Drug Discovery Today [Epub ahead of print] PubMed abstract
• Evans, R; Coussens, AK; Kriston-Vizi, J; Chain, BJ and Noursadeghi, M (2011)
  The effect of vitamin D on monocyte biology: a physiological perspective.
  Immunology 135, 88 Abstract No.226
• Finney, BA; Schweighoffer, E; Navarro-Núñez, L; Bénézech, C; Barone, F; Hughes, CE; Langan, SA; Lowe, KL; Pollitt, AY; Mourao-Sa, D; Sheardown, S; Nash, GB; Smithers, N; Reis e Sousa, C; Tybulewicz, VLJ and Watson, SP (2011)
  CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.
  Blood [Epub ahead of print] PubMed abstract
• Freitas do Rosário, AP; Lamb, T; Spence, P; Stephens, R; Lang, A; Roers, A; Muller, W; O'Garra, A and Langhorne, J (2011)
  IL-27 promotes IL-10 production by effector Th1 CD4⁺ T cells: a critical mechanism for protection from severe immunopathology during malaria infection.
  Journal of Immunology [Epub ahead of print] PubMed abstract
• Hirota, K; Ahlfors, H; Duarte, JH and Stockinger, B (2011)
  Regulation and function of innate and adaptive interleukin-17-producing cells.
  EMBO Reports [Epub ahead of print] PubMed abstract
• Hogan, T; Shuvaev, A; Commenges, D; Callard, R; Thiebaut, R and Seddon, B (2011)
  A common programme of proliferative control for diverse homeostatic responses by T cells.
  Immunology 135, 211 Abstract No.815
• Marshall, D and Seddon, B (2011)
  The role of cytokine and TCR signaling in the development of regulatory T cells.
  Immunology 135, 54 Abstract No.56
• Moss, DK; Remarque, EJ; Faber, BW; Cavanagh, DR; Arnot, DE; Thomas, AW and Holder, AA (2011)
  Plasmodium falciparum merozoite surface protein (MSP) 1₁₉-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion and intracellular parasite development.
  Infection and Immunity [Epub ahead of print] PubMed abstract
• Parker, HJ; Piccinelli, P; Sauka-Spengler, T; Bronner, M and Elgar, G (2011)
  Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers.
  BMC Genomics 12, 637 PubMed abstract
• Pastore, A and Temussi, PA (2011)
  The two faces of Janus: functional interactions and protein aggregation.
  Current Opinion in Structural Biology 22, [Epub ahead of print] PubMed abstract
• Pearson, C; Tung, S; Seddon, B and Powrie, F (2011)
  Cytokine requirements in models of inflammatory bowel disease.
  Immunology 135, 119 Abstract No.357
• Pericleous, C; Garza-Garcia, A; Murfitt, L; Driscoll, PC; Isenberg, DA; Pierangeli, SS and Giles, I (2011)
  Profiling sub-types of anti-2 glycoprotein I and anti-domain I antibodies may distinguish between different clinical phenotypes of the antiphospholipid syndrome.
  Arthritis and Rheumatism 63, 23
• Schnoeller, C; Loebbermann, J; Durant, L; Johansson, C; Thornton, H; O'Garra, A and Openshaw, P (2011)
  Roles for IL-10 in RSV infection.
  Immunology 135, 199 Abstract No.492
• Sinclair, C and Seddon, B (2011)
  A feed-forward regulatory circuit tunes TCR signalling sensitivity and controls the CD4 versus CD8 SP lineage decision.
  Immunology 135, 48 Abstract No.14
• Stockinger, B; Potocnik, A and Hirota, K (2011)
  Development and modulation of IL-17 immune responses.
  Immunology 135, 23 Abstract No.282
• Tamuri, AU; dos Reis, M and Goldstein, RA (2011)
  Using site-wise mutation-selection models to estimate the distribution of selection coefficients from phylogenetic data.
  Genetics [Epub ahead of print] PubMed abstract
• van der Loeff, IS and Seddon, B (2011)
  The role of Zap70 in naïve CD8 T cell survival.
  Immunology 135, 59 Abstract No.268
• Wilhelm, C; Hirota, K; Stieglitz, B; Van Snick, J; Tolaini, M; Lahl, K; Sparwasser, T; Helmby, H and Stockinger, B (2011)
  Novel sources of IL-9 in lung inflammation.
  Immunology 135, 128 Abstract No.886

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