MRC National Institute for Medical Research, London
Science for Health
Steve Gamblin awarded Feldberg Foundation prize for 2012
14 January 2011
The Feldberg Foundation was established in 1961 by Professor Wilhelm Feldberg, a former Head of the Division of Physiology and Pharmacology at NIMR. The Foundation promotes scientific contact between German and English scientists within the sphere of experimental medical research, in particular in physiology, pharmacology and related topics, primarily through scientific exchange lectures.
Each year one German and one British scientist is awarded a prize, the amount of which is an indication of Feldberg's wish that the recipients should be outstanding in their particular field. Each recipient gives a lecture in each other's country (and since 1999, up to three additional lectures). The prizes are awarded to German scientists resident in Germany and to British scientists resident in the United Kingdom. The prizes for 2011 and 2012 have been announced, and Dr Gamblin (pictured) has been awarded the 2012 prize.
Steve Gamblin uses a combination of structural, biophysical and functional studies to understand molecules involved in diseases such as influenza, diabetes and cancer. Work on influenza is focused on the two major surface glycoproteins of the virus, hemagglutinin (HA) and neuraminidase (NA). Work relevant to diabetes has focused on understanding the structural and mechanistic basis of energy sensing and regulation by the human AMP-dependent Protein Kinase (AMPK). Gamblin’s laboratory also has a long-term interest in how covalent modifications of histones, the molecules that package DNA into chromatin, regulate gene expression through epigenetic mechanisms.
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