News: research

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ADP is a universal signal of low energy in cells

11 November 2011

Researchers at NIMR have discovered the metabolic signal that allows the adaptation of budding yeast for growth on low glucose or non-glucose sources.  The research is published in Cell Metabolism

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Crystal structure reveals unusual enzyme activity of HIV-1 restriction factor

07 November 2011

Scientists at NIMR and the University of Manchester have moved closer to understanding how the SAMHD1 protein helps to block the human immunodeficiency virus HIV-1. The research is published online in Nature.

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RNA regulatory networks in Mycobacterium tuberculosis

07 November 2011

Scientists from NIMR and the Sanger Institute have explored RNA regulatory networks in Mycobacterium tuberculosis. The research is published in PLoS Pathogens

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Vitamin D deficiency associates strongly with tuberculosis in Cape Town

31 October 2011

Researchers at NIMR and in Cape Town have found that Vitamin D deficiency is extremely common in black Africans living in Cape Town, South Africa and is associated with susceptibility to tuberculosis infection.  The research is published in PNAS.

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Eat your broccoli

13 October 2011

Scientists at NIMR have found that nutrients found in vegetables such as broccoli help to maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. The research is published in Cell.

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Towards a better understanding of lung inflammation

10 October 2011

Scientists at NIMR have generated a mouse strain that has helped to reveal a new cell type involved in allergic lung disease. The research is published in Nature Immunology

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The battle to define embryonic territories

22 September 2011

In a collaboration with Angela Nieto's group in Alicante, Spain, scientists at NIMR have discovered that two transcription factors, Snail and Sox3, directly repress each other in a battle to decide which cells will undergo epithelial to mesenchyme transition. The research is published in Developmental Cell.

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Neurogenic potential of glial cells in the gut of adult animals

25 August 2011

Scientists at NIMR have discovered that glial cells within the gut of adult animals are capable of generating enteric neurons in response to injury. The research is published in the Journal of Clinical Investigation.

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Cell survival depends on relative Wnt signalling

15 August 2011

Scientists at NIMR have shown that the relative - not absolute - activity of a key signalling pathway determines cell survival. The research is published in Developmental Cell.

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Malaria in the field

12 August 2011

An NIMR postdoctoral scientist was awarded a Winston Churchill Travelling Fellowship to work on malaria in Malaysia.

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