News: research

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A key developmental and stem cell regulator also acts in tumorigenesis

20 January 2012

Research published by NIMR scientists describes how a gene known to play a role in normal development and stem cells can contribute to the processes of transformation leading to cancer. The work is published in Cancer Research.

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Gene network that builds tissues revealed

20 January 2012

A network of interacting genes that control how cells are organised into tissues has been revealed by scientists at NIMR and UCL. The research is published in Cell. 

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Quantitative imaging of metabolism: seeing is believing

20 January 2012

Researchers at NIMR and Harvard Medical School have developed a method for visualizing and quantitating the metabolism of molecules inside a single cell. The research is published in Nature.

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Platelets influence the formation of lymphatic vessels

13 January 2012

Scientists at NIMR and at the University of Birmingham have shown how platelets affect the development of the circulatory system. The research is published in Blood.

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An unexpected mechanism of FHA function in DNA-repair signalling

13 January 2012

A recent paper by NIMR scientists and collaborators in Switzerland, Denmark and the UK, published in Nucleic Acids Research, provides new insights into the mechanisms by which the detection and repair of double-stranded DNA breaks is signalled to the cell-cycle machinery.

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A protein from blood vessels in the brain enhances production of new neurons

10 January 2012

Research published by NIMR scientists describes a new factor that may help with methods to stimulate brain repair after trauma or disease. The work is published in Proceedings of the National Academy of Sciences, USA.

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Long-term experience-dependent plasticity in an endocrine system

03 January 2012

Together with colleagues in Montpellier, France, scientists at NIMR have demonstrated that long-lasting experience-dependent plasticity is a key feature of endocrine cell populations and permits functional adaptation of hormone secretion. The research is published in Nature Communications.

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How compensatory evolution leads to multi-drug-resistant TB

19 December 2011

Research at NIMR and the Swiss Tropical and Public Health Institute has described a set of compensatory mutations in the RNA polymerase genes of rifampicin-resistant M. tuberculosis. The research is published in Nature Genetics.

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Shedding of surface protein helps malaria parasite evade antibodies

16 December 2011

Scientists at NIMR have found that shedding of AMA1, a protein involved in red blood cell invasion by the malaria merozoite, is essential and helps the parasite to avoid attack by antibodies. The research is published in PLoS Pathogens.

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IL7 - License to live: how training can improve your chances of survival

16 November 2011

A new study from scientists at NIMR reveals how the life span of T lymphocytes is programmed during their cell development in the thymus. The research is published in Science Signaling

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