News: research

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Kenyan fieldwork helps to advance malaria research

31 August 2012

Sophie Roetynck, a postdoc in Jean Langhorne’s group in the Division of Parasitology at NIMR, works on the immunology of malaria infection in humans. Her work on the CD4 T cell responses to the infection has involved extensive fieldwork in Kenya.

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Neuronal biophysical diversity is an emergent property of brain circuit organization

23 July 2012

NIMR researchers have shown that neuronal excitability is stereotypic for mitral cells from the same olfactory network, indicating that local circuits are functionally adapted to process subtly distinct information. The research is published in Nature.

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New mosquito insectary at NIMR

20 July 2012

A new insectary has been built at NIMR to provide a platform for breeding and preparing mosquitoes for studying rodent malaria, used as a model for human infection. 

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Targeting axons to a synaptic layer

12 July 2012

NIMR scientists have uncovered a highly precise strategy that enables axons to target to a distinct synaptic layer using the visual system of Drosophila as a model. This study is published in Neuron.

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Novel X-inactivation RNA discovered

18 June 2012

Researchers at NIMR and their collaborators have identified the gene responsible for X chromosome inactivation in the second largest class of mammals, the metatherians (marsupials). The research is published in Nature.

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High-throughput experimental technique interest group

07 June 2012

A high-throughput interest group at NIMR has been widened to include participation by scientists from LRI and from other partners in The Francis Crick Institute.

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How to discriminate between active and latent TB

07 June 2012

Researchers from NIMR have helped to find a way to distinguish patients with active TB from those with latent infection. The research is published in PLoS ONE.

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Protein evolution

29 May 2012

NIMR and University of Colorado scientists have discovered that proteins predictably adjust through coevolutionary processes when an amino acid is replaced. The research is published in Proceedings of the National Academy of Sciences, USA.

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Opposing guidance cues on positioning cell clusters

24 May 2012

Scientists at NIMR have shown that two different signals act as opposing guidance cues in collective cell migration.  This work is published in Development.

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New candidates for anti-malaria and anti-leishmaniasis drugs

14 May 2012

A partnership between industry and academia has made available new selective inhibitors of protozoan N-myristoyl transferase to accelerate the development of drugs to treat malaria and leishmaniasis. The research is published in PLoS Neglected Tropical Diseases.

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