MRC National Institute for Medical Research, London
Science for Health
News: research
Th17 cells are essential for intestinal homeostasis
11 March 2013
NIMR scientists have shown that Th17 cell plasticity in Peyer’s patches regulates IgA induction. The research is published in Nature Immunology.
Insights into vertebrate evolution, from the sea lamprey
06 March 2013
NIMR scientists have taken part in a large collaborative project to analyse the genome of the sea lamprey. The research is published in Nature Genetics.
Receptor cross-talk controls B cell survival
28 February 2013
Researchers at NIMR have shown that B cell survival depends on unexpected cross-talk between a receptor for the BAFF cytokine and the B cell antigen receptor. The work is published in Immunity.
Neuronal subtype determined by graded activity of the transcription factor Ascl1
15 February 2013
Researchers at NIMR have shown that neurons can be made different from one another by expressing either high or low quantities of the protein, Ascl1. The research is published in Current Biology.
Hepcidin’s role in malaria
08 February 2013
Scientists at NIMR and in Nigeria have found that hepcidin levels are lower in cases of severe malaria. The research was published in Blood.
Evolution of influenza virus binding receptors
21 January 2013
Researchers at NIMR have shown that recent influenza A(H3N2) viruses have very different receptor binding properties compared with older viruses. The research is published in PNAS.
A novel set of mycobacterial antigens
03 January 2013
NIMR researchers have explored a novel means to identify antigenic targets that might contribute to a vaccine against TB. The research is published in Journal of Immunology and is a featured article.
Culture and transfection of an emerging malaria pathogen
02 January 2013
Researchers at NIMR have adapted Plasmodium knowlesi to continuous culture in human erythrocytes, providing a new, genetically tractable model for malaria research. The work is published in the Proceedings of the National Academy of Sciences, USA.
An AC/DC circuit for developmental biology
14 December 2012
Researchers at NIMR and UCL have used mathematical modelling to show how a network of genes can produce either spatial patterns or oscillations in developing tissues. The research is published in Journal of the Royal Society Interface.
A new link between p27 and stem cell biology
11 December 2012
NIMR researchers, working with Manuel Serrano from CNIO (Madrid), have found that the tumor suppressor p27 contributes to transcriptional repression of the “stemness” transcription factor SOX2. The research is published in Cell Stem Cell.
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