News: research

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A spumaviral Gag-Env complex

10 May 2013

Structural and virological studies by NIMR scientists have revealed the nature of an essential Gag-Env interaction that is required for spumaretrovirus egress from the cell. The research is published in PLOS Pathogens.

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What controls egress of the malaria parasite from infected red blood cells?

10 May 2013

NIMR scientists have identified components of a signalling pathway that leads to release of the malaria pathogen from parasitised red blood cells. The research is published in PLOS Pathogens.

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A better way to find biomarkers in infectious disease

09 May 2013

NIMR scientists have developed a new statistical technique for exploring infectious diseases. The research is published in PLOS Computational Biology.

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How pandemic flu viruses gain the ability to infect humans

24 April 2013

Researchers at NIMR have shown how structural changes mediate the transmissibility of flu viruses in humans. The research is published in Nature.

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A better method for recombinant protein production

17 April 2013

NIMR scientists have developed a novel methodology to produce milligram quantities of highly pure, catalytically active recombinant protein complex. The research is published in Biochemical Journal.

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Regulatory pathways involved in mitotic exit

12 April 2013

In collaboration with researchers from the USA, NIMR scientists have revealed a molecular mechanism that contributes to the release of dividing cells from mitosis. The work is published in Science.

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Obesity study shows involvement of inflammation and a factor made by white blood cells

11 April 2013

NIMR scientists contributed to a study showing that an imbalance between an enzyme and its inhibitor can cause inflammation, contributing to obesity, diabetes, and related pathologies. The research is published in Cell Metabolism.

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Mouse development consortium wins £5m Wellcome Trust Strategic Award

19 March 2013

A consortium of institutions, led by researchers from NIMR, has been granted a Wellcome Trust Strategic Award to identify genes essential for mouse development and the origins of developmental diseases and birth defects in humans.

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A new genetic tool for studying malaria

19 March 2013

NIMR scientists have successfully applied a conditional recombination system to Plasmodium falciparum. The research is published in Molecular Microbiology.

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Genes that control the connectivity of enteric neurons

11 March 2013

NIMR scientists have identified genes affecting enteric neuronal connectivity and a possible pathogenetic mechanism for disorders associated with abnormal intestinal motility. The research is published in Journal of Clinical Investigation.

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