Science for Health
19 August 2013
Andy Oates studied biochemistry at the University of Adelaide, then completed his PhD at the Ludwig Instiute for Cancer Research in Melbourne, working under Andrew Wilks and Leornard Zon. After a postdoc with Robert Ho, at Princeton and the University of Chicago, in 2003 he moved to set up his own lab at the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden.
His work on the genetic clock that controls the development of segments in vertebrate embryos has shown that when we change the frequency of this clock, we alter the size and number of segments in the animal, so the timing of the clock is instructing the anatomy of the body.
His research group at NIMR incudes biologists, engineers, and physicists, using a combination of molecular genetics, quantitative imaging, and theoretical analysis. His aim is to provide insights into the way our body axis segments. His work will also suggest how rapid changes in gene activity are controlled and coordinated in other important contexts such as inflammation and stem cell differentiation, where oscillations have just recently been discovered. His group is beginning to explore new transgenic tools that allow them to follow the oscillations of the segmentation clock in real time.
We're very pleased and excited to welcome the Oates lab to NIMR. Andy's interdisciplinary research is at the forefront of the field. The presence of clock like mechanisms in many different areas of biology means that Andy's work on oscillation s in embryos not only sheds light on an important developmental process but has broad implications across the fields of developmental and cell biology. We look forward to working with him at NIMR and in the future at the Francis Crick Institute.
James Briscoe and Jean-Paul Vincent, joint heads of the Division of Developmental Biology
© MRC National Institute for Medical Research
The Ridgeway, Mill Hill, London NW7 1AA