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Morphogen gradients not needed for proliferation
07 October 2009
NIMR scientists have shown that proliferation of cells in the Drosophila wing does not require a gradient of the morphogen Wingless. The research is published in Science Signaling.
John Eccleston (1943-2009)
02 October 2009
It is with great sadness that we learnt of the death of John Eccleston at the early age of 66.
Conserved structure in DNA-damage response proteins
02 October 2009
NIMR scientists have revealed the structure of a protein that plays important roles in the DNA-damage response. The article is published in Cell.
Dating the origin of the 1918 influenza pandemic virus
01 October 2009
NIMR scientists have studied the sequence of the virus that caused the 1918 influenza pandemic and have estimated its date of introduction into mammals and into the human population. The research is published in Journal of Molecular Evolution.
3-D images of cell organelles
30 September 2009
NIMR scientists have used electron cryomicroscopy to image assemblies of the von Willebrand Factor directly in endothelial cells. The research is published in Proceedings of the National Academy of Sciences.
Learning about tuberculosis immunity from adversity
29 September 2009
NIMR scientists have shown that in the context of overall improved tuberculosis antigen specific T cell responses it is the central memory rather than effector memory response that best correlates with decreased susceptibility. This has important implications for vaccine design, as well as monitoring vaccine efficiency.
A clue to how avian flu jumps to humans
29 September 2009
NIMR scientists have determined the X-ray structures of receptor complexes of the H2 hemagglutinin from the 1957 ‘Asian flu’ pandemic and compared them with similar complexes from the other two flu pandemics of the twentieth century. The article is published online in Proceedings of the National Academy of Sciences, USA.
Mapping heart mutations in Xenopus frogs
29 September 2009
NIMR scientists have completed the first mapping of a genetic mutation in the frog Xenopus tropicalis.
Polycomb proteins and repressive histone marks
22 September 2009
NIMR scientists have described how repressive chromatin domains are maintained and transmitted. The article is published online in Nature.
Natural Killer master gene identified
14 September 2009
NIMR scientists in collaboration with NIMR visiting researcher, Hugh Brady of Imperial College London, have identified the Natural Killer cell 'master gene' thus creating a mouse model that lacks this lineage of lymphoid cells. The research is published in Nature Immunology.
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