Vincent group ::

Signals, trafficking and boundaries in developing epithelia of Drosophila

Our lab is interested in the role of signals in epithelial pattern formation and morphogenesis. We follow two main interests:

formation and maintenance of boundaries within developing epithelia
trafficking of one specific signal, that encoded by wingless, the founding member of the Wnt family

All our work is with Drosophila.

Franch-Marro, X; Marchand, O; Piddini, E; Ricardo, S; Alexandre, C and Vincent, JP (2005)
Glypicans shunt the Wingless signal between local signalling and further transport.
Development 132, 659-666 PubMed abstract
Marygold, SJ and Vincent, JP (2003)
Armadillo levels are reduced during mitosis in Drosophila.
Mechanisms of Development 120, 157-165 PubMed abstract
Alexandre, C and Vincent, JP (2003)
Requirements for transcriptional repression and activation by Engrailed in Drosophila embryos.
Development 130, 729-739 PubMed abstract
Vincent, JP and Dubois, L (2002)
Morphogen transport along epithelia, an integrated trafficking problem.
Developmental Cell 3, 615-623 PubMed abstract
Vincent, JP and Magee, T (2002)
Argosomes: membrane fragments on the run.
Trends in Cell Biology 12, 57-60 PubMed abstract
Pfeiffer, S; Ricardo, S; Manneville, JB; Alexandre, C and Vincent, JP (2002)
Producing cells retain and recycle wingless in Drosophila embryos.
Current Biology 12, 957-962 PubMed abstract

[Page last updated 20 May 2005]